V1 is a septal lead, and with septal wall infarctions, there are ST-segment changes seen on ECG.
On ECG, we see ST-segment changes on lead V2 with septal wall infarcts. Lead V2 is known as a septal lead.
The left anterior descending coronary artery, or LAD, is also termed the "widow maker," because it supplies 45-55% of the left ventricle. Occlusion of this artery can lead to septal wall infarct.
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