Stable Angina
- Chest Pain with Exertion
 - Relieved within 15 Minutes
 - ST Depression
 - Nitroglycerin
 - Up to 3 Doses q 5 Minutes
 - Rest
 - Antiplatelet Medication
 - CABG
 - Angioplasty
 
Unstable Angina
- Chest Pain with Rest or Exertion
 - Limits ADLs
 - > 15 Minutes
 - Less Likely Relieved by Nitroglycerin
 - ST Depression
 - Fatigue
 - Acute Coronary Syndrome (ACS) Treatment
 - Emergency Treatment
 
Myocardial Infarction Assessment
- Substernal Chest Pain
 - Crushing or Dull Sensation
 - Arm, Jaw, and Neck
 - > 20 Minutes
 - Unrelieved by Nitro
 - Palpitations
 - Diaphoresis
 - Fear of Impending Doom
 - Nausea and Vomiting
 - Shortness of Breath
 - Monitor for Arrhythmias
 
Myocardial Infarction Diagnosis
- 12 Lead ECG
 - ST Elevation
 - Q Wave
 - T Wave Inversion
 - Troponin T and I
 - CK-MB
 - Early ECG
 - Cardiac Stress Test
 
Myocardial Infarction Interventions
- Morphine
 - Oxygen
 - Nitrates
 - Aspirin
 - Thrombolytics (tPA)
 - Cardiac Catheterization
 - Stent Placement
 - Angioplasty
 - Coronary Artery Bypass Grafting (CABG)
 - Decrease Modifiable Risk Factors
 - Resuming Activity (Physical, Sexual)
 
Cardiac Catheterization
- Fluttering Sensation
 - Contrast Media
 - NPO 6-12 Hours
 - Bed Rest
 - Assess Circulation
 - Assess for Bleeding
 - Monitor Vital Signs
 
Cardiac Enzyme Evaluation: Troponin
- Cardiac Muscle Injury
 - Detection in Blood: 4 Hours
 - Peak: 24 - 36 Hours
 - Return to Normal: 5 - 14 Days
 - Most Specific for Cardiac Muscle
 - Treat Aggressively
 
Cardiac Enzyme Evaluation: Creatine Kinase CK-MB
- Skeletal or Cardiac Muscle Injury
 - Onset: 4-8 Hours
 - Peak: 12-24 Hours
 - Return to Normal: 2-3 Days
 
Cardiac Enzyme Evaluation: Myoglobin
- Skeletal or Cardiac Muscle Injury
 - Onset: 1 - 4 Hours
 - Peak: 12 Hours
 - Return to Normal: 24 Hours
 - Elevation After 24 Hours: Reinfarction
 
TIMI Score (Thrombolysis In Myocardial Infarction)
- Mortality Predictor
 - Unstable Angina or NSTEMI
 - 2 Week Risk of Death and Ischemic Events
 - Age Greater or Equal to 65
 - Markers Elevated
 - EKG ST Changes (Greater or Equal to 0.5mm)
 - Risk Factors for CAD (Coronary Artery Disease)
 - Ischemia (2 Anginal Events in 24 Hours)
 - Coronary Artery Disease (CAD)
 - Aspirin Use in the Last 7 Days
 
Evolution of Myocardial Infarction and Complications
- Arrhythmia
 - Fibrinous Pericarditis
 - Papillary Muscle Rupture
 - Interventricular Septum Rupture
 - Ventricular Pseudoaneurysm
 - Ventricular Free Wall Rupture
 - True Ventricular Aneurysm
 - Dressler Syndrome
 - Left Ventricular Failure
 
12 Lead Contiguous Leads - Anterior Wall MI
- Lead V3
 - Lead V4
 - Left Anterior Descending (LAD)
 
12 Lead Contiguous Leads - Septal Wall MI
- Lead V1
 - Lead V2
 - Left Anterior Descending (LAD)
 
12 Lead Contiguous Leads - Inferior Wall MI
- Lead II
 - Lead III
 - Lead aVF
 - Right Coronary Artery (RCA)
 
12 Lead Contiguous Leads - Lateral Wall MI
- Lead I
 - Lead aVL
 - Lead V5
 - Lead V6
 - Circumflex
 
Brugada Syndrome
- Defective Myocardial Sodium Channels
 - Predominance in Asian Males
 - Autosomal Dominant
 - Pseudo-Right Bundle Branch Block Pattern
 - Persistent ST Elevations in Leads V1-V2
 - Risk of VTACH and Sudden Cardiac Death
 - Syncope
 - ICD
 - Antiarrhythmics
 
Ischemia and Vulnerable Tissues
- Brain
 - MCA-ACA and MCA-PCA Interface
 - Heart
 - Subendocardium of Left Ventricle
 - Kidney
 - Proximal Tubule
 - Thick Ascending Limbs of the Loop of Henle
 - Liver
 - Central Vein
 - Colon
 - Splenic Flexure
 - Rectosigmoid Junction