Master Brugada Syndrome with Picmonic for Medicine

Brugada syndrome shows a predominance in Asian males.

Brugada syndrome has an autosomal dominant inheritance pattern, though it exhibits variable expression.

Typically, the ECG findings of Brugada syndrome consist of a pseudo-right bundle branch block and persistent ST segment elevation in leads V1 to V2. On EKG, this is seen as a coved ST-elevation in the precordial leads V1-V2, as is seen in a right bundle branch block, however there is no widening of the S wave in the lateral leads V5-V6 as is seen in a right bundle branch block, hence the "pseudo".

A pseudo-right bundle branch block pattern and persistent ST elevations in leads V1-V2 is the characteristic finding on EKG associated with Brugada syndrome.

Patients with Brugada syndrome are at risk for experiencing long runs of ventricular tachycardia, in which the ventricles beat at an excessively fast rate that does not allow for adequate ventricular filling during diastole, resulting in significantly compromised cardiac output.

Patients with Brugada syndrome may experience syncopal episodes due to sustained runs of ventricular tachycardia, causing significantly reduced cardiac output to the brain.

Patients with Brugada syndrome who have experienced syncope or episodes of Vtach should have an implantable cardioverter-defibrillator or ICD implanted.

Anti-arrhythmics, namely quinidine and amiodarone, may be indicated in some patients with Brugada in addition to an ICD