Master NRTIs for HIV (Drug Names) with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

NRTIs for HIV (Drug Names)

Nerd-ties with HIV-bandaid
Picmonic
NRTIs include two groups of medications; nucleoside reverse transcriptase inhibitors and nucleotide reverse transcriptase inhibitors. Nucleoside analog medications that disrupt viral DNA replication include Didanosine (DDI), Emtricitabine (FTC), Abacavir (ABC), Lamivudine (3TC), Stavudine (d4T), and Zidovudine (ZDV). In contrast, Tenofivir (TDF) is a nucleotide analog medication.
8 KEY FACTS
NUCLEOSIDE ANALOG
DEALSZ
DEALSZ-tag

DEALSZ is an acryonym used to organize the nucleoside analog NRTIs. D-E-A-L-S-Z; Didanosine, Emtricitabine, Abacavir, Lamivudine, Stavudine, and Zidovudine.

Didanosine (DDI)
DD-eyes

Didanosine (DDI) works as an analog to adenosine. The most common adverse events with didanosine are diarrhea, nausea, vomiting, abdominal pain, fever, headache and rash. Patients can also develop peripheral neuropathy and non-cirrhotic portal hypertension.

Emtricitabine (FTC)
Electricity-bone

Emtricitabine is a nucleoside reverse transcriptase inhibitor, which works as an analog to cytidine. It is used to treat HIV, but also has clinical activity against Hepatitis B Virus. Side effects are rare, but include diarrhea, headache, nausea, and rash. More severe side effects include hepatotoxicity and lactic acidosis.

Abacavir (ABC)
ABC-cadaver

Abacavir (ABC) is a nucleoside analog reverse transcriptase inhibitor. This medication is an analog of guanosine, and is given orally, and has a high bioavailability. Common reactions include nausea, headache, fatigue, vomiting, hypersensitivity reaction, diarrhea, fever/chills, depression, rash, anxiety, URI, ALT, AST elevated, hypertriglyceridemia, and lipodystrophy.

Lamivudine (3TC)
Lamb-voodoo

Lamivudine is an analogue of cytidine. It can inhibit HIV reverse transcriptase, as well as the reverse transcriptase of hepatitis B virus.

Stavudine (d4T)
Staff-voodoo

Stavudine is an analog of thymidine, which inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It then leads to termination of DNA replication by incorporating into the DNA strand. Side effects of this drug include peripheral neuropathy and lipodystrophy, and for this reason it is less commonly used in patients from developed countries.

Zidovudine (ZDV)
Zombie-dove

Zidovudine, or ZDV, is also called AZT, for azidothymidine. It works by selectively inhibiting HIV's reverse transcriptase, the enzyme that the virus uses to make a DNA copy of its RNA. Side effects include anemia, neutropenia, hepatotoxicity, cardiomyopathy, and myopathy. Due to viral resistance, this is usually given as part of HAART.

NUCLEOTIDE ANALOG
Tenofovir (TDF)
Tin-of-ears

Tenofivir is a nucleotide analogue reverse transcriptase inhibitor (NRTI), that inhibits reverse transcriptase. Reverse transcriptase is a crucial viral enzyme in human immunodeficiency virus and hepatitis B virus infections. The most common side effects associated with tenofovir include nausea, vomiting, diarrhea, and weakness. Renal complications include acute renal failure, Fanconi syndrome, proteinuria, or tubular necrosis.

Unlock all 8 facts & definitions with Picmonic Free!

JOIN FREE

Take the NRTIs for HIV (Drug Names) Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.