Depression is the most common indication for Bupropion. Many times, this drug is combined with SSRI therapy.
The second most common use for Bupropion is smoking cessation. This drug is proven to reduce the severity of nicotine cravings and withdrawal symptoms.
This drug still has an unclear mechanism of action, but yields increased levels of dopamine and norepinephrine. A proposed mechanism driving smoking cessation is by block of nicotinic acetylcholine receptors in the brain.
The stimulant side effects of this drug include tachycardia and insomnia in some patients.
This drug is known to lower the seizure threshold, leading to epileptic seizure in patients.
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