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Ovarian Cystadenocarcinoma

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Ovarian Cystadenocarcinoma

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Ovarian Cystadenocarcinoma

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Cystadenocarcinoma is the most common type of malignant ovarian tumor, often detected late in patients. Tumors arise from ovarian surface epithelium and are either of serous or mucinous type. Serous-type comprises 45% of ovarian tumors and are often bilateral with psammoma bodies. Mucinous tumors have mucus-secreting epithelium and mucinous material may travel to and accumulate in the peritoneal cavity. BRCA-1 and Lynch syndrome are hereditary risk factors, and increased CA 125 is a common indication for ovarian cancer.
10 KEY FACTS
Non-germ Cell Tumor
Non-germy ovary

Cystadenocarcinoma arise from ovarian surface epithelium and are either serous or mucinous.

Mucinous
Mucus

Mucinous cystadenocarcinoma present with mucus-secreting epithelium and cysts containing these accumulated secretions.

Peritoneal Spread
Parrot-toe

Mucinous cystadenocarcinoma patients may experience pseudomyxoma peritonei, where mucinous material from the ovarian tumor accumulates within the peritoneal cavity.

Serous
Seltzer

Cystadenocarcinomas with serous lining comprise 45% of ovarian tumors and are often bilateral.

Psammoma Bodies
Samoan

Serous cystadenocarcinoma tumors show papillary structures with round calcium deposits called psammoma bodies.

Bilateral
Bi-ladders

Tumors are often bilateral.

Malignant
Malignant-man

Cystadenocarcinoma is the most common malignant ovarian tumor.

Stromal Invasion
Invading-Straw-man

Stromal invasion is often seen in cystadenocarcinoma, with tumors spreading past the basement membrane and into the stromal tissue.

CA 125
CA-125 road sign

Increased CA 125 is a common ovarian cancer marker. While not suitable for screening, it is effective for monitoring progression.

BRCA-1 and Lynch Syndrome
Breast-of-Chicken for Lunch

BRCA-1 and Lynch syndrome are hereditary risk factors for cystadenocarcinoma. BRCA-1 is more associated with serous cystadenocarcinoma.

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