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Auer Rods

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Auer Rods

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Auer Rods

Hourglass on a Rod
Picmonic
Auer rods are azurophilic granular needles consisting of the enzyme myeloperoxidase. They are seen in leukemic blast cells and are virtually diagnostic of AML.
4 KEY FACTS
Azurophilic granular needles in leukemic blasts
Purple Arizona with Grain Needles in Leukemia-Luke's Blasting-cell

Auer rods stain purple and are present in leukemic blast cells.

Disseminated Intravascular Coagulation (DIC)
Dice

Release of Auer rods can cause DIC (disseminate intravascular coagulation), a pathological activation of coagulation mechanisms.

Acute Myelogenous Leukemia (AML)
American Monkey Legion (AML)

Auer rods are seen in AML and their presence is virtually diagnostic of AML.

All-trans Retinoic Acid (Vitamin A)
All-train with red-tins of Acidic-lemons (Viking-Apple)

This is used in the treatment of AML and allows leukemic blasts to mature and differentiate further.

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