NEW LOWER PRICES - ACT FAST
Medicine (MD/DO)
/
Courses
/
Pathology
/
Immunodeficiency Disorders
/
IL-12 Receptor Deficiency

Master IL-12 Receptor Deficiency with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

DOWNLOAD PDF
IL-12 Receptor Deficiency

Recommended Picmonics

picmonic thumbnail
Bruton's Agammaglobulinemia
picmonic thumbnail
Common Variable Immunodeficiency
picmonic thumbnail
Selective IgA Deficiency
picmonic thumbnail
Thymic Aplasia (DiGeorge Syndrome)
picmonic thumbnail
Hyper IgE Syndrome

IL-12 Receptor Deficiency

Interlocked (12) Dozen carton with Broken Receptor
Picmonic
IL12 receptor deficiency is a congenital T-cell immunodeficiency which results in a decreased Th1 response. IL-12 is essential for the differentiation of non-specific T-cells into a Th1 cellular mediated response. Without this activating molecule, the Th1 response is insufficient. The patient is prone to disseminated mycobacterial infections including tuberculosis.
5 KEY FACTS
PATHOPHYSIOLOGY
IL-12 Secreted by Macrophages
IL12 Key Held by Mac-man

IL-12 is responsible for the differentiation of T-cells into Th1 cells and is secreted by macrophages in the immune response.

Decreased Th1 Response
Down-arrow trapped Tennis-balls with (1) Wands

IL-12 is responsible for the differentiation of T-cells into Th1 cells. This is an essential piece to the cell mediated response.

Decreased IFN Gamma
Down-arrow Grandma with IFN-ray-gun

IFN-gamma is a key initiator for the Th1 cellular response, which is secreted after activation by IL-12, and mounts a strong response. Due to the limitations with IL-12, the IFN-gamma is in short supply and the immune response is decreased.

SIGNS AND SYMPTOMS
Mycobacterial Infections
Bacteria with Mics

The Th1 response is responsible for cellular immunity, which is particularly essential for the immune response against mycobacterial pathogens.

Salmonella
Salmon

Host defense against salmonella also depends heavily upon the functional integrity of mononuclear phagocytes and their interaction with T-cells.

DOWNLOAD PDF

Take the IL-12 Receptor Deficiency Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.