Master Common Variable Immunodeficiency with Picmonic for Medicine

Overall, common variable immunodeficiency is characterized by a defect in B cell maturation, leading to decreased number of plasma cells and low levels of immunoglobulins in the serum. The number of B cells is normal, however.

Overall, common variable immunodeficiency is characterized by a defect in B cell maturation, leading to decreased number of plasma cells and low levels of immunoglobulins in the serum. This leads to inadequate response to pathogens and recurrent infections.

Overall, common variable immunodeficiency is characterized by a defect in B cell maturation, leading to decreased number of plasma cells and low levels of immunoglobulins in the serum. This leads to inadequate response to pathogens and recurrent infections.

Because the patient is not able to produce sufficient antibodies in response to exposure to pathogens, they are at increased risk of recurrent sinopulmonary infections.

There is an increased risk of autoimmune diseases in patients with Common variable immunodeficiency, with a risk of up to 25%. Most commonly, autoimmune destruction of platelets or red blood cells is seen.

Common variable immunodeficiency may predispose individuals to developing lymphomas, although the exact mechanism is poorly understood.