Medicine (MD/DO)
Autoimmune Disorders
Ankylosing Spondylitis

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Ankylosing Spondylitis

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Ankylosing Spondylitis

Anchor Spine
Ankylosing spondylitis is a chronic inflammatory disease, which mainly effects the spine and sacroiliac joints of the pelvis. It can eventually lead to fusion of the vertebrae ("bamboo spine"), and has a high association with HLA-B27. This disease is more prevalent in males and usually presents at the age of 23. Patients with this chronic inflammatory disease may also have uveitis and aortic regurgitation, as they are commonly associated with ankylosing spondylitis.
Chronic Inflammatory Arthritis
Crone King-Arthur In-Flames

This disease is a chronic inflammatory arthritis which effects the axial skeleton. It is seronegative, meaning there is no rheumatoid factor (circulating IgG antibody). Ankylosing spondylitis mainly affects the spine and sacroiliac joints.

"Bamboo Spine"

This arthritic disease causes chronic inflammation of the spine. Some patients experience eventual fusion of the vertebrae and complain of rigidity of the spine. Radiologic imaging in this scenario shows fusion which is termed "bamboo spine."

(HLA) Hula Bee (27) Bomber

Human leukocyte antigen B27 is strongly associated with inflammatory diseases known as spondyloarthropathies, including ankylosing spondylitis, psoriatic arthritis, and Reiter's syndrome.


Roughly 40% of patients with ankylosing spondylitis also experience uveitis, which is inflammation of the anterior chamber of the eye. Patients complain of eye redness, pain, photophobia and vision loss.

Aortic Regurgitation
A-orca Regurgitating

Though less commonly associated, many patients also experience aortic regurgitation with ankylosing spondylitis.


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