Master Picornavirus with Picmonic for Medicine

These viruses do not have an envelope covering their protein capsid.

The picornaviruses have RNA genomes.

This virus has an icosahedral protein capsid with 20 identical equilateral triangular faces.

Single stranded positive sense linear viruses have their genome directly utilized as mRNA. Host ribosomes translate the RNA genome directly into a single protein that is modified by host and viral proteins to form the various proteins necessary for replication.

These viruses encode all of their viral proteins in one single, long, open reading frame and form one large polypeptide that is cleaved by proteases.

Rhinoviruses are different than the entero picornaviruses because rhinoviruses replicate better at 33 degrees C and are inactivated or destroyed by low pH conditions. Therefore, rhinoviruses infect and are restricted to the nose and throat and cause the common cold.

This virus is the causative agent of poliomyelitis, which can infect the central nervous system, preferentially infecting and destroying motor neurons causing muscle weakness and paralysis.

Coxsackievirus is a picornavirus that can cause a wide variety of human diseases including hand foot and mouth disease, aseptic meningitis, and febrile pharyngitis. This virus is also associated with type 1 diabetes and dilated cardiomyopathy.

This virus is a member of the picornavirus family and is usually asymptomatic but can cause an acute hepatitis. Like the other enteroviruses, it is transmitted via fecal-oral route. This virus does not cause a chronic hepatitis.

Echovirus is a common cause of aseptic meningitis, which is inflammation of the meninges without a pyogenic bacterial source.

Echovirus is a common cause of aseptic meningitis, which is inflammation of the meninges without a pyogenic bacterial source.