🍪
'Tis the season sale SAVE 30% now
Medicine (MD/DO)
/
Courses
/
Microbiology
/
Antifungals
/
Amphotericin B

Amphotericin B and Side Effects Mnemonic Video

In this mnemonic video, you'll learn all about the Amphotericin B medication, including how it works, what it is used for, and the potential side effects.

DOWNLOAD PDF
Amphotericin B

Amphotericin B

Amphibian-terminator (B) Bee
Picmonic
Amphotericin B is a polyene medication, which works by binding to ergosterol in fungal cell membranes. It forms membrane pores, causing electrolytes to leak, killing the fungal cell. It is used for serious, systemic mycoses. It can lead to the side effects of fever and chills, nephrotoxicity, arrhythmias, anemia and IV phlebitis.
6 KEY FACTS
INDICATIONS
Systemic Mycosis
Systemic Mic-fungus

Amphotericin B is used to treat various systemic fungal infections. Examples include patients who are critically ill, comorbidly infected, or immunocompromised with suspected Cryptococcus.

Fungal Meningitis
Fun-guy Men-in-tights

Amphotericin B is used to treat fungal meningitis, such as cryptococcal meningitis.

Last Resort for Protozoan infections
Last Resort Propeller-protozoa

Amphotericin B can also be used intravenously to treat otherwise-untreatable parasitic protozoan infections like visceral leishmaniasis and amoebic meningoencephalitis from Naegleria Fowleri.

MECHANISM
Polyene
Polly-lean

This medication works as a polyene as it binds to ergosterol and forms membrane pores.

Binds Ergosterol
Binding to Eggo-stairs

After binding to ergosterol, Amphotericin B forms membrane pores and allows leakage of electrolytes, resulting in fungal cell death.

Forms Membrane Pores
Membrane Holes

After binding to ergosterol, Amphotericin B forms membrane pores, which allows leakage of electrolytes, ultimately killing the fungal cell.

DOWNLOAD PDF

Recommended Picmonics

picmonic thumbnail
Amphotericin B Side Effects & Toxicity
picmonic thumbnail
Azoles (Ketoconazole)
picmonic thumbnail
Griseofulvin
picmonic thumbnail
Terbinafine
picmonic thumbnail
Echinocandins

Take the Amphotericin B Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,990,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.