Ace Your PANCE Prep Pearls: 2nd Ed. (2017) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Physician Assistant (PA) Students
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PANCE Prep Pearls: 2nd Ed. (2017) | Physician Assistant (PA) School Study Aid
Nephrotic Syndrome
- Signs and Symptoms
- Massive Proteinuria > 3.5g per Day
- Edema
- Increased risk of infection
- Thromboembolism
- Hyperlipidemia
- Fatty casts
1 min
Minimal Change Disease
- Pathophysiology
- Nephrotic
- Most Common in Children
- May be Triggered by Recent Infection or Immune Stimulus
- Diagnosis
- On Electron Microscopy (EM) See Foot Process (Podocyte) Effacement
- On Light Microscopy (LM) See Normal Glomeruli
- Loss of Negative Charge
- Selective Loss of Albumin
- Treatment
- Responds to Corticosteroids
2 mins
Focal Segmental Glomerulosclerosis
- Most Common Cause of Nephrotic Syndrome in Hispanic People and African Americans
- Associated with Sickle Cell Disease and HIV
- Associated Interferon Therapy and Heroin Abuse
- Histopathology
- LM Segmental Sclerosis and Hyalinosis
- EM Focal Damage of Visceral Epithelial Cells
- IF Negative
- Signs & Symptoms
- Microscopic Hematuria
- Nonselective Proteinuria
- Considerations
- Poor Prognosis
2 mins
Membranous Glomerulonephritis
- Characteristics
- Nephrotic
- Diagnosis
- LM Thickening of Capillary and Glomerular Basement Membrane (GBM)
- EM Spike and Dome Appearance with Subepithelial Deposits
- IF Granular
- Primary
- Phospholipase A2 Receptor Autoantibodies
- Secondary
- NSAIDS
- Gold
- Solid Tumors
- Hepatitis B Virus (HBV)
- Lupus
3 mins
