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Pharmacological Nursing | Nursing (RN) School Study Aid


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Reproductive Pharmacology
11 Picmonics to Learn | 22 mins

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Raloxifene
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Agonist in Bone
Antagonist in Breast and Uterus
Indications
Osteoporosis
Breast Cancer Prophylaxis
Uterine Fibroids
Side Effects
Hot Flashes
Thromboembolism
2 mins
RhoGam [Rho(D) Immune Globulin]
Indications
Antepartum Prevention at 28 weeks
Suppress Antibody Production
Mechanism of Action
Lysis of Fetal RBC in Maternal Bloodstream
Side Effects
Myalgia and Lethargy
Considerations
Negative Coombs Test
Standard Dose 300 mcg
Microdose 50 mcg
Blood Product
2 mins
Magnesium Sulfate
Mechanism
Muscle Relaxant
Indications
Preterm Labor Contractions
Preeclampsia
Side Effects
Warm Feeling
Hypotension
Decreased Deep Tendon Reflexes (DTRS)
Decreased Respiratory Rate
Decreased Urine Output
Paralytic Ileus
Antidote
Calcium Gluconate
2 mins
Leuprolide
Mechanism
GnRH Agonist (Pulsatile Use)
GnRH Antagonist (Continuous Use)
Upregulates FSH And LH
Downregulates FSH And LH
Indications Pulsatile
Infertility
Indications Continuous
Prostate Cancer
Precocious Puberty
Uterine Fibroids
Endometriosis
Side Effects
Anti-androgenic Effects
2 mins
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
Mechanism
Smooth Muscle Contraction
Vasoconstriction
Indications
Migraine
Postpartum Hemorrhage
Side Effects
Nausea and Vomiting
Severe Hypertension
Tachycardia
Considerations
2nd Line Agent
2 mins
Oxytocin (Pitocin)
Mechanism of Action
Increase Uterine Contractions
Indications
Labor Induction
Control Postpartum Hemorrhage
Side Effects
Uterine Rupture
Water Intoxication
Contraindications
Fetal Lung Immaturity
Cervix Not Ripened
Active Genital Herpes Infection
Considerations
Use Lowest Dose
IV Pump
3 mins
Carboprost (Hemabate)
Mechanism
Prostaglandin F2-alpha Analog
Smooth Muscle Contraction
Indications
Postpartum Hemorrhage
Abortion
Side Effects
GI Distress
Hypertension
Fever
Bronchoconstriction
Considerations
Identify Cause of Fever
2 mins
Dinoprostone and Misoprostol
Mechanism
Prostaglandins
Indications
Promote Cervical Ripening
Prevent GI Ulcers
Medical Abortion
Side Effects
Fetal Distress
Hyperstimulation of Uterus
Considerations
Vaginal Insertion
Give Before Induction of Labor
2 mins
Terbutaline (Brethine)
Mechanism of Action
Beta-2 Agonists
Indications
Asthma
Tocolytic
Side Effects
Hypotension
Tremor
Tachycardia
Pulmonary Edema
Hyperglycemia
2 mins
Mifepristone, Ulipristal (Antiprogestins)
Mechanism of Action
Progesterone Receptor Antagonist
Indications
Mifepristone
Pregnancy Termination With Misoprostol
Ulipristal
Emergency Contraception
Side effects
Abdominal Pain
Vomiting
Diarrhea
other mechanisms of action
At High Doses: Cortisol Antagonist
2 mins
Clomiphene
Indications
Infertility
Polycystic Ovarian Syndrome (PCOS)
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Hypothalamus
Estrogen Antagonist
Increased GnRH, LH and FSH Secretion
Induction of Ovulation
Side Effects
Multiple Gestations
Visual Disturbances
Hot Flashes
3 mins

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