Nondepolarizing Neuromuscular Blocking Drugs
- Names Include "Cur"
- Competitive Antagonists
- Acetylcholine Competition
- Reversal of Blockade
- Neostigmine, Edrophonium
Succinylcholine
- Inducing Paralysis
- Neuromuscular Blocking Drugs
- Motor Nicotinic Receptor
- ACh Receptor Agonist
- Depolarization
- Phase I (Paralysis Non-reversible)
- Phase II (Paralysis Reversible)
- Neostigmine (Reversal Agent)
Parkinson's Drugs
- Decreased Dopamine
- Increased Acetylcholine
- BALSA Acronym
- Bromocriptine
- Amantadine
- Levodopa
- Selegiline
- Antimuscarinics
Levodopa/Carbidopa (Sinemet)
- Increases Dopamine in Brain
- Parkinson's Disease
- Nausea and Vomiting
- Arrhythmias
- Dyskinesia
- Psychosis
- Orthostatic Hypotension
- Report Uncontrolled Movements
- Darkened Sweat or Urine
- Off and On Phenomenon
Memantine
- Alzheimer's Disease
- NMDA Receptor Antagonist
- Prevents Excitotoxicity
- Confusion
- Hallucinations
Donepezil
- Alzheimer's Disease
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Nausea and Vomiting
- Dizziness
Sumatriptan
- Short Half-Life
- 5-HT Agonist
- Inhibits Trigeminal Nerve Activation
- Induces Vasoconstriction
- Migraine
- Cluster Headache
- Increased Risk of Serotonin Syndrome
- Paresthesias
- Coronary Vasospasm
- Prinzmetal's Angina
- Coronary Artery Disease (CAD)
Gabapentin
- Seizure Treatment
- Peripheral Neuropathy
- Postherpetic Neuralgia
- Bipolar Disorder
- Migraine Prophylaxis
- Inhibits Voltage-Gated Ca2+ channels
- GABA Analog
- Ataxia
- Sedation
Codeine
- Opioid Receptor Agonist
- Mild to Moderate Pain
- Cough Suppressant
- Sedation
- Constipation
- Miosis
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
Morphine
- Opioid Receptor Agonist
- Pain
- Myocardial Infarction
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
Meperidine (Demerol)
- Opioid Receptor Agonist
- Moderate to Severe Pain
- Post Anesthesia Shivering
- Tremors
- Constipation
- CNS Depression
- Sedation
- Short Term Administration
- Increased Risk Serotonin Syndrome
- Does NOT cause Miosis
- Renal Failure Increases Toxicity Risk
Naloxone (Narcan)
- Competitive Opioid Receptor Antagonist
- Opioid Induced CNS Depression
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Repeated Dosing Often Required
Tramadol
- Chronic Pain
- Weak Opioid
- Inhibit Serotonin and NE reuptake
- Increased Risk of Seizure
Butorphanol
- Migraine
- Severe Pain
- Labor
- Partial Agonist at Mu and Full Agonist at Kappa Receptors
- Less Respiratory Depression
- Withdrawal Symptoms
Acetaminophen-Hydrocodone (Vicodin)
- Combination Analgesic
- Opioid Receptor Agonist
- Hydrocodone
- Reversible Inhibition of COX
- Acetaminophen
- Moderate to Severe Pain
- CNS Depression
- Respiratory Depression
- Hepatotoxicity
- Addiction
Oxycodone
- Opioid Receptor Agonist
- Refractory Pain
- Respiratory Depression
- Constipation
- CNS Depression
- Addiction
- Naloxone
Serotonin Syndrome Assessment
- Restlessness
- Diaphoresis
- Tachycardia
- Hypertension
- Diarrhea
- Hyperthermia
- Decreased Level of Consciousness
- Muscle Rigidity
- Seizure and Coma
- Cyproheptadine
Suvorexant
- Orexin Receptor Antagonist
- Insomnia
- CNS Depression
- Headache
- Abnormal Dreams
- Contraindicated in Narcolepsy
- Avoid in Liver Disease
Fentanyl
- Opioid Receptor Agonist
- High Potency
- Anesthesia Induction
- Chronic Pain
- Breakthrough Pain
- CNS Depression
- Respiratory Depression
- Constipation
- Miosis
- Addiction
Buprenorphine-Naloxone (Suboxone)
- Combination Drug
- Partial Opioid Receptor Agonist (Buprenorphine)
- Opioid Receptor Antagonist (Naloxone)
- Opioid Use Disorder
- CNS Depression
- Diaphoresis
- Hypotension
- Low Abuse Potential
Acetazolamide
- Glaucoma
- Altitude Sickness
- Pseudotumor Cerebri
- CHF
- Metabolic Alkalosis
- Carbonic Anhydrase Inhibitor
- Sodium Bicarbonate (NaHCO3) Diuresis
- Metabolic Acidosis
- Paresthesias