Master Memantine with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.


Memantine is an NMDA receptor antagonist drug, which helps prevent excitotoxicity in patients with Alzheimer's disease. It is a glutamergic antagonist at NMDA receptors. This medication works by halting an influx of Ca2+, preventing excitotoxicity to neurons. Neuronal excitotoxicity is mediated by Ca2+, which activates intracellular enzymes, leading to cell destruction. Thus, by halting this influx, memantine shows symptomatic improvement in patients. This drug has been shown to have a modest effect on moderate and severe Alzheimer's cases, while having little benefit in mild cases of Alzheimer's disease. Though rare, patients taking memantine can experience the side effects of confusion and hallucinations.
Alzheimer's Disease

Memantine is an NMDA receptor antagonist drug which helps prevent excitotoxicity in patients with Alzheimer's.

NMDA Receptor Antagonist
NMDA Receptor Ant-toga

Memantine is a glutamatergic antagonist at NMDA receptors.  This action allows to impede an influx of Ca2+, halting excitotoxicity to neurons. This drug is low affinity and short-acting with a modest effect.

Prevents Excitotoxicity
Blocking Excited-X-toxic nerves

By antagonizing NMDA receptors, excitotoxicity is prevented in neurons. Excitotoxicity is mediated by Ca2+ which activates intracellular enzymes, leading to cell destruction.


An adverse effect of treatment with memantine is confusion in patients.


Patients taking memantine can suffer from hallucinations.

Unlock all 5 facts & definitions with Picmonic Free!

Take the Memantine Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,240,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.