In this mnemonic video, you'll learn about the different medications that can result in cytochrome p450 inhibition. Then follow-up with spaced repetition quizzes to improve recall of these commonly tested p450 inducers.
DOWNLOAD PDFGriseofulvin is an orally administered antifungal drug for treatment of fungal infections of skin and nails. This drug interferes with microtubule function and therefore disrupts mitosis of fungal organisms.
Phenytoin is a commonly used antiepileptic drug. It acts to suppress abnormal brain activities via blockade of sodium channels. It is also a class 1B anti-arrhythmic
Carbamazepine is an anticonvulsant and mood stabilizing drug. It is commonly used for epilepsy and trigeminal neuralgia
Rifampin is used mainly for the treatment of active Mycobacterium tuberculosis. It acts by inhibiting the DNA dependent RNA polymerase
Barbiturates are drugs that depress the central nervous system by increasing the duration of chloride channel opening and thus decreasing neuron firing. They are commonly used for anxiety and seizures.
Chronic alcohol use causes the liver to increase transcription and translation of p450 enzymes to metabolize the toxic byproducts of alcohol and induces the p450 system
St. John's Wort is best known as an herbal treatment commonly used for mild depression
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