Beat The Heat SAVE 25% NOW
Medicine (MD/DO)
Antiepileptic Drugs
Vigabatrin and Tiagabine

Master Vigabatrin and Tiagabine with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Vigabatrin and Tiagabine

Recommended Picmonics

picmonic thumbnail
Benzodiazepines Overview
picmonic thumbnail
Short-acting Benzodiazepines
picmonic thumbnail
Benzodiazepine Antidote
picmonic thumbnail
Phenobarbital (Barbiturates)
picmonic thumbnail

Vigabatrin and Tiagabine

V-goose-bat-train and Tiger-goose-bin
Vigabatrin and tiagabine are antiepileptic medications. They work to increase GABA concentrations by inhibiting its degradation and reuptake. These drugs are indicated for infantile spasms and partial (focal) seizures. The major side effect of vigabatrin and tiagabine is permanent visual loss (black box warning).
Increases GABA Concentration
Up-arrow GABA-goose

Vigabatrin and tiagabine increase GABA concentrations in the central nervous system. This helps to prevent excessive neuronal firing seen in seizures and epilepsy syndromes.

Inhibits GABA Degradation (Vigabatrin)
Inhibiting-chains on Degrading Goose

Vigabatrin (brand name Sabril) inhibits GABA degradation by inhibiting GABA transaminase, an enzyme that breaks down GABA. By blocking this function, GABA concentration increases.

Inhibits GABA Reuptake (Tiagabine)
Inhibiting-chains on GABA-goose and Reuptake-tube

Tiagabine (brand name Gabitril) works by inhibiting GABA reuptake into presynaptic neurons. This results in higher synaptic availability of GABA that will be able to bind to receptors on the postsynaptic membrane.

Infantile Spasms
Infant Muscle-man-spaceship

Infantile spasms, also known as West Syndrome, is an epilepsy syndrome of infancy and childhood which is most commonly seen in the first year of life. It is characterized by mental retardation and hypsarrhythmia on interictal EEG. Vigabatrin can be used as monotherapy to treat this condition.

Partial (Focal) Seizure
Partial Caesar with Focusing-magnifying-glass

Vigabatrin is used as adjunctive therapy for adult and older pediatric patients with refractory complex partial seizures. Tiagabine is similarly indicated in patients younger than 12 years of age.

Permanent Visual Loss (Vigabatrin)

Vigabatrin may cause permanent, concentric peripheral visual field loss. The risk is dose-dependent. This is thought to occur from drug-induced injury of retinal photoreceptors, ganglion cells, and their axons. Visual field and ophthalmological testing are needed before treatment and routinely checked every 3 months during treatment. Because of this side effect, this medication is labeled with a black box warning from the FDA.


Take the Vigabatrin and Tiagabine Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,910,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.