Master Aspirin with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.


Recommended Picmonics

picmonic thumbnail
Aspirin Poisoning (Salicylism) Assessment
picmonic thumbnail
picmonic thumbnail
Warfarin Antidotes
picmonic thumbnail
Heparin Mechanisms
picmonic thumbnail
Heparin Indications


Also known as acetylsalicylic acid, aspirin is an anti-inflammatory, antipyretic, analgesic and antiplatelet drug. It is classified as an NSAID; however, its mechanism of action differs from other NSAID’s because it irreversibly inhibits COX-1 and COX-2 in comparison with other NSAID’s, which reversibly inhibit COX-1 and COX-2.

It is believed to reduce fever via blockage of Prostaglandin E2 (PGE2).

Pain and Headache
Pain-bolt and Head-egg-lump

It is believed to have pain-killing effects due to its inhibition of both COX-1 and COX-2.

Cardiovascular Disease (CAD)
Heart Diseased

Due to its antiplatelet effects, aspirin has been demonstrated to be effective for prevention of MI and ischemic stroke in those with existing cardiovascular disease (CVD) and those without CVD.

Irreversible inhibition of COX-1 and COX-2
Locked Inhibiting-chains on Cock (1) Wand and Cock (2) Tutu

Aspirin irreversibly inhibit COX-1 and COX-2 and results in inhibition of production of prostaglandins (PG) and thromboxanes (TX).

Suppress Thromboxanes and Prostaglandins
Suppressing Trombone-axes and P-rasta

This prevents PGs from performing their role in inflammatory responses, pain processing and fever production and TXs from causing platelet aggregation.


Aspirin is classified as an NSAID but it performs irreversible, not reversible inhibition of COX-1 and COX-2.

Reye's Syndrome
Rays from aspirin bottle

Administration of aspirin to children with viral infection is associated with microvesicular steatosis of hepatocytes, hepatoencephalopathy and potentially death. Causality has not yet been established.


Chronic aspirin toxicity can occur in individuals chronically taking 3g or more daily. This may result in ringing in the ears (tinnitus) possibly due to activation of cochlear NMDA receptors.

Peptic Ulceration
Gas Ulcer-volcano

PG’s produced by COX-1 help maintain the protective GI mucosal barrier in the stomach and intestines. Blockage of these PG’s via COX-1 inhibition can result in gastric ulcers.

Mixed Acidosis/Alkalosis
Acidic-lemon and Elk-loser

Aspirin toxicity can result in initial respiratory alkalosis due to hyperventilation and then metabolic acidosis. This presents as a mixed respiratory alkalosis and metabolic acidosis.


Aspirin can cause renal ischemia due to decreased renal blood flow, renal papillary necrosis or interstitial nephritis (acute or chronic).


Take the Aspirin Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,620,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.