Master Aluminum Hydroxide with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Aluminum Hydroxide

Aluminum-foil Hydra-OHs
DikeHAfifi
Aluminum hydroxide is an antacid used for patients with pyrosis and other gastrointestinal distress. Side effects include constipation, hypophosphatemia, osteodystrophy, proximal muscle weakness, and seizures. Exercise caution when administering aluminum hydroxide with other drugs because it is a chelating agent.
7 KEY FACTS
CLINICAL USE
Antacid
Ant-acid-bottle

Aluminum hydroxide is an antacid. It can reduce pepsin production, which is involved in HCl secretion and protects the stomach from alcohol and other irritants. In the stomach, aluminum hydroxide dissociates to Al3+ and OH-. The hydroxide group will bind free protons creating an insoluble salt (e.g., aluminum chloride) and water, increasing stomach pH.

SIDE EFFECTS
Constipation
Corked Con-toilet

Aluminum hydroxide can relax gastrointestinal smooth muscles, resulting in constipation. The tendency to cause constipation makes most manufacturers combine it with magnesium hydroxide that has a laxative effect.

Hypophosphatemia
Hippo-phosphate-P

Aluminum hydroxide can bind phosphate in the gut lumen, resulting in aluminum phosphate formation, which is insoluble. This binding causes a reduction of phosphate in the blood, which leads to hypophosphatemia.

Osteodystrophy
Ostrich-disc-trophy

Aluminum is absorbed in the GIT and transported rapidly to bone. An extended period of aluminum exposure can deposit aluminum in the bone, cause an accumulative effect. It interrupts mineralization and bone cell growth activity. Aluminum overload can suppress the production of osteoblasts, resulting in low bone formation, causing osteodystrophy. This feature is also known as aluminum-related osteodystrophy.

Proximal Muscle Weakness
P-proximal Drooping Muscles

Aluminum hydroxide may cause symmetrical weakness of the proximal upper or lower extremities. Patients will have difficulties in combing, rising from a seat, climbing stairs, reaching high objects, and washing hair.

Seizures
Caesar

Another side effect is seizure. Aluminum can accumulate in gray matter, causing encephalopathy.

CONSIDERATIONS
Chelating Agent
Cleats-on Agent

Aluminum is a trivalent metal cation that can bind or chelate certain drugs, resulting in decreased absorption of other drugs. Consequences of this are reduced bioavailability of the other drugs.

Unlock all 7 facts & definitions with Picmonic Free!

Take the Aluminum Hydroxide Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,240,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.