Master Subacute Thyroiditis Pathophysiology with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Subacute Thyroiditis Pathophysiology

Sub-acute-angle with Thigh-droid-on-fire
sesanch1
Subacute thyroiditis is a self-limiting disease characterized by a triphasic response. This disease begins with the thyrotoxic phase, where damaged follicular cells release pre-formed colloid. This typically lasts from 2-8 weeks. Following this is the hypothyroid phase, where thyroid hormone synthesis is decreased because of the damage. This lasts about 2-8 weeks as well. A euthyroid phase comes last, which is characterized by recovery of the thyroid gland.
10 KEY FACTS
CHARACTERISTICS
Self-Limiting
Self-Limiting

Subacute thyroiditis is largely self-limited. However, some patients experience relapses and permanent hypothyroidism occurs in 15% of cases.

Triphasic Response
(3) Tree

Subacute thyroiditis, which involves inflammation of the thyroid, manifests as a triphasic response. Each phase varies in duration and includes the thyrotoxic, hypothyroid, and euthyroid phases.

THYROTOXIC PHASE
Thyrotoxic Phase
Thigh with Toxic-green-glow

The first phase of the triphasic response is referred to as the thyrotoxic phase. This phase typically last 2-8 weeks and is due to damage of the follicular cells and the release of pre-formed colloid or stored T3/T4.

Damaged Follicular Cells Release Pre-formed Colloid
Damaged Follicles Releasing Coals

The thyrotoxic phase is due to damage of the follicular cells and the release of stored T3/T4 (i.e. pre-formed colloid).

2-8 Weeks
(2) Tutu and (8) Ball on Weekly-newspaper

The thyrotoxic and hypothyroid phases typically last 2-8 weeks.

HYPOTHYROID PHASE
Hypothyroid Phase
Hippo-thigh-droid

The second phase of the triphasic response is the hypothyroid phase, which can be permanent in ~15% of subacute granulomatous thyroiditis cases. The hypothyroid phase involves the depletion of pre-formed colloid along with the impaired synthesis of new thyroid hormones as a result of follicular cell damage.

Decreased Thyroid Hormone Synthesis
Down-arrow with Thigh-droid with Harmonica

The hypothyroid phase involves the depletion of pre-formed colloid and as a result leads to the impaired synthesis of new thyroid hormones (i.e. colloid) due to the damage of the follicular cells.

2-8 Weeks
(2) Tutu and (8) Ball on Weekly-newspaper

The thyrotoxic and hypothyroid phases typically last 2-8 weeks.

EUTHYROID PHASE
Euthyroid Phase
Letter-U Thigh-droid

The last phase of the triphasic response - the euthyroid phase - involves recovery of thyroid functioning along with pathological changes no longer being visible in the thyroid gland.

Thyroid Gland Recovery
Thyroid in Recovery Chair

The euthyroid phase involves the recovery of the thyroid along with pathological changes no longer being visible in the thyroid gland.

Unlock all 10 facts & definitions with Picmonic Free!

JOIN FREE

Take the Subacute Thyroiditis Pathophysiology Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 1,040,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medical (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.