Brenner tumors are non-germ cell tumors, appearing encapsulated and grossly pale, yellow-tan in color.
Histologically, Brenner tumor tissue appears similar to transitional-type epithelium with fibrous stroma, as seen in bladder tissue.
The vast majority of Brenner tumors are benign and unilateral. These tumors may vary greatly in size, ranging from 1 to 30 cm in presentation. These tumors are rarely malignant.
Brenner tumor cells have distinctive coffee-bean shaped nuclei, a description derived from the longitudinal nuclear grooves and fibrous stroma seen on histology.
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