Master Retinitis Pigmentosa with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Retinitis Pigmentosa

Red-tin-eyes Piggy-bank
Arwa_Bohra
Retinitis pigmentosa (RP) is a disease that results in dystrophic tissue architecture of the retina and/or retinal pigment epithelium. Retinal degeneration occurs in a hereditary fashion. Clinical features include night blindness, defects in color and contrast vision, and tunnel vision (peripheral visual field loss). RP is associated with abetalipoproteinemia, Kearns-Sayre syndrome, and Refsum disease. On fundoscopy, RP classically looks like bone spicule-shaped retinal deposits. Ultimately, this disease leads to permanent blindness.
9 KEY FACTS
CHARACTERISTICS
Hereditary Retinal Degeneration
Hair-Red-Kid with Red-Tins-Damaged

RP is a hereditary disease that causes retinal degeneration. Several genes may cause RP, but mutations in the rhodopsin gene that code for an important G-protein coupled receptor in photoreceptor cells is implicated in the majority.

CLINICAL FEATURES
Night Blindness
Nightgown and Blinds-over-eyes

Night blindness, or nyctalopia, is due to the degeneration of rods. It can be assessed by measuring the time delay in dark adaptation or slow waves on electroretinogram.

Contrast and Color Defects
Contrasting-Convict and Colors-Broken

As the degeneration of rods proceeds, contrast sensitivity decreases. Finer details like shadows and depth become more difficult to perceive. Colors also start appearing less distinct.

Tunnel Vision
Tunnel View

In late or advanced stages, peripheral retinal degeneration can result in peripheral visual field loss, or tunnel vision.

ASSOCIATIONS
Abetalipoproteinemia
A-beta-fish-lips-protein

Abetalipoproteinemia is a malabsorption disease that results from mutations in the microsomal triglyceride transfer protein (MTTP) gene. It causes deficiencies of apolipoproteins B-48 and B-100.

Kearns-Sayre Syndrome
Corn Syrup

Kearns-Sayre syndrome is classified as an inborn error of metabolism disease. It is a mitochondrial myopathy characterized by ophthalmoplegia, retinitis pigmentosa, and cardiac defects.

Refsum Disease
Referee

Refsum disease is a hereditary motor and sensory neuropathy. It is due to an accumulation of phytanic acid and can cause retinitis pigmentosa.

DIAGNOSIS
Bone Spicule-shaped Retinal Deposits
Bone Towers with Black-smoke and Spiculated-moon

On fundoscopy, several bone spicule-shaped retinal deposits may be seen. They progress from the periphery to the macula.

CONSIDERATIONS
Permanent Blindness
Permed-Hair with Blinds-Over-Eyes

Ultimately, this disease leads to permanent blindness as there is no cure.

Unlock all 9 facts & definitions with Picmonic Free!

JOIN FREE

Take the Retinitis Pigmentosa Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 1,050,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medical (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.