Hyperacute rejection occurs within minutes.
Hyperacute transplant rejections occur within minutes.
In this type of rejection, an antibody-mediated rejection occurs due to the presence of preformed antidonor antibodies in the transplant recipient.
Acute rejection, which occurs weeks later, leads to a cell-mediated rejection process due to cytotoxic T lymphocytes reacting against foreign MHCs. Interestingly, it can also lead to an antibody-mediated immune (humoral) response.
Acute rejections occur within weeks of transplantation.
Acute rejection may occur due to a cell-mediated rejection process, where cytotoxic T lymphocytes react against foreign MHCs. Acute rejection may also occur due to an antibody-mediated (humoral) response.
In chronic rejection, which occurs months to years after transplant, organ atrophy is caused by T cell and antibody-mediated vascular damage.
Chronic rejection is observed months to years after transplant.
In this type of transplant rejection, T cell and antibody-mediated vascular damage leads to organ ischemia, causing atrophy.
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