This tumor is most commonly found in the cerebellum and can present with symptoms of ataxia and gait disturbance.
This tumor is associated with Von Hippel Lindau syndrome, which is a mutation of the VHL tumor suppressor gene. A mutation in this gene produces multiple tumors and cysts throughout the body and is associated with hemangioblastomas.
Retinal angiomas are benign tumors that can occur sporadically or in association with Von Hippel Lindau disease. High vascularization can cause vascular leakage and eventually retinal detachment in the eye.
Hemangioblastomas are highly vascular and are known to produce erythropoietin.
Due to the ability to produce erythropoietin, this tumor can cause a secondary polycythemia, which is an increase in the RBC count independent of stem cells.
Histologically this tumor contains foamy cells, which are large cells containing lipid droplets.
This tumor is highly vascular and can be seen in its gross and histological appearance, demonstrating large amounts of capillary networks.
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