Lead V3 is an anterior lead, and shows pathologic Q waves and ST-segment changes with anterior wall infarcts.
V4 is an anterior lead, which shows pathologic Q waves and ST-segment elevation in cases of anterior wall MI.
The left anterior descending artery (LAD), or the widow maker, provides descending blood supply to large areas of the heart. This means that if these arteries gets abruptly and completely occluded it will cause a massive heart attack that will likely lead to a sudden death.
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