Master Eosinophilic Esophagitis with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Eosinophilic Esophagitis

Eosinophilic-Eagle With Sarcophagus
Nicholazk
Eosinophilic esophagitis is an allergic inflammatory condition of the esophagus that involves the infiltration of the esophageal tissue by eosinophils. This condition likely involves an allergic response to food allergens and is frequently associated with atopic disease. Eosinophilic esophagitis typically presents with dysphagia due to the narrowing of the lumen from inflammation, edema, and strictures. Diagnosis is typically made by endoscopy with biopsy demonstrating eosinophilic infiltrates in the esophageal tissue. This condition is typically unresponsive to GERD treatment and requires elimination diet and/or pharmacotherapy with proton pump inhibitors and topical corticosteroids.
8 KEY FACTS
CHARACTERISTICS
History of Atopic Disease
A-top-hat Diseased-guy

About 50% of patients with eosinophilic esophagitis also have a history of some type of atopic disease (e.g., food allergies, asthma, allergic rhinitis, eczema). While the precise mechanism is unknown, it seems like allergen mediated immune system activation is the driving force of this condition.

SYMPTOMS
Dysphagia
Dice-Fajita

Eosinophil buildup and chronic inflammation of the esophageal tissue can cause narrowing of the lumen due to swelling and/or strictures. This can lead to difficulty swallowing (dysphagia). Patients often present with dysphagia to solids as the narrowing is usually not severe enough to cause difficulties swallowing liquids.

DIAGNOSIS
Endoscopy with Biopsy
Endoscope with Biopsy-needle

Endoscopy with biopsy is the diagnostic study of choice for the confirmation of eosinophilic esophagitis. Characteristic findings on endoscopy include longitudinal mucosal furrows, fixed esophageal rings, narrowed lumen, corrugated mucosa, and strictures.

Eosinophilic Infiltrate
Eosinophilic-Eagles In a Sarcophagus

Eosinophils are white blood cells that increase in response to allergen mediated immune system activation. In patients with eosinophilic esophagitis, eosinophils infiltrate and accumulate in the esophageal tissue. This buildup of eosinophils can lead to chronic inflammation of esophageal mucosa. Biopsy of the tissue reveals at least 15 eosinophils per high-power field infiltrating esophageal mucosa.

Unresponsive to GERD Therapy
Ant-acid-bottle and H2 Block-man Ignored By Girdle-Girl

GERD therapy (e.g., antacids, H-2-receptor blockers) is usually ineffective in patients with eosinophilic esophagitis. Dietary modifications (e.g., removal of the allergen) is crucial for the effective control of disease activity, and proton pump inhibitors or topical steroids can be used as initial pharmacologic agents.

INTERVENTIONS
Elimination Diet
Food Being Eliminated

One of the initial treatment options for eosinophilic esophagitis is elimination diet. A six-food elimination diet or a four-food elimination diet are both viable options. Foods that are eliminated typically include common allergens (e.g., dairy products, wheat, egg, soy). This approach to treatment should be coordinated with a dietician since elimination diet can result in restriction of calories and nutrients.

Proton Pump Inhibitors (PPIs)
Proton Pump with Inhibiting-chains

Proton pump inhibitors are one of the first-line medications for eosinophilic esophagitis. The clinical response should be evaluated after an 8-week course of treatment. At the end of the 8-week course, endoscopy is also frequently done to evaluate histologic response.

Topical Glucocorticoids
Top-hat Quarter-on-steroids

Topical glucocorticoids are also first-line medications for eosinophilic esophagitis.  Fluticasone treatment for 4-8 weeks is typically recommended. The drug is sprayed in the back of the mouth, and the patient is instructed to swallow so that the drug coats the mucosal surface of the esophagus.

Unlock all 8 facts & definitions with Picmonic Free!

JOIN FREE

Take the Eosinophilic Esophagitis Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 1,050,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medical (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.