Master Inflammatory Carcinoma of Breast with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Inflammatory Carcinoma of Breast

Flames on Car-gnome and Breasts
sesanch1
Inflammatory breast carcinoma/cancer (IBC) is an invasive malignancy of breast tissue. It characteristically invades dermal lymphatic vessels, which can be seen on histology. On physical examination of the breast, this disease may mimic mastitis or Paget disease of breast. Key clinical findings include peau d'orange, breast tenderness, and bloody nipple discharge. Unfortunately, inflammatory breast carcinoma has a poor prognosis.
7 KEY FACTS
CHARACTERISTICS
Invasive Malignancy
Invasive Malignant-man

Inflammatory carcinoma of the breast is considered a rare, aggressive, advanced form of breast cancer that is characterized by dermal lymphatic invasion of tumor cells.

Invades Dermal Lymphatic Vessels
Invading Deer-mouse Lymph-limes and Vessels

Histologically, inflammatory carcinoma involves extensive blockage of the lymphovascular dermis with carcinoma cells. In other words, the tumor cells invade the dermal lymphatics.

Mimics Mastitis and Paget Disease of Breast
Mime Mast on Fire and Pageant-sash

Inflammatory carcinoma can often be confused with other similar conditions e.g. mastitis and Paget disease of the breast. Inflammatory invasive carcinoma is not necessarily an inflammatory condition as inflammation is not present. Instead, the underlying pathophysiology involves diffuse infiltrates of the dermis.

CLINICAL FEATURES
Peau d'Orange
Peeled Orange

The presence of a tumor leads to impaired lymphatic drainage and subsequent lymphedema. This leads to tightening of the skin which leaves the skin of the breast resembling an orange peel. The impaired lymphatic drainage can also cause hair follicle pitting and erythema.

Breast Tenderness
Breast Tenderizer

Breast tenderness is associated with inflammatory carcinoma. This can be useful in terms of diagnosis as most breast cancers, if palpable, will be non-tender.

Bloody Nipple Discharge
Bloody Discharge from Nipple

Inflammatory carcinoma of the breast can also present with bloody nipple discharge.

CONSIDERATIONS
Poor Prognosis
Gravestones

Inflammatory carcinoma is associated with a poor prognosis due to the time of presentation relating to likely metastases. Thus, there is a 50% survival rate at 5 years from diagnosis.

Unlock all 7 facts & definitions with Picmonic Free!

Take the Inflammatory Carcinoma of Breast Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,180,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.