Master Primary Biliary Cholangitis (Primary Biliary Cirrhosis) Diagnosis and Treatment with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Primary Biliary Cholangitis (Primary Biliary Cirrhosis) Diagnosis and Treatment

Recommended Picmonics

picmonic thumbnail
Primary Biliary Cholangitis (Primary Biliary Cirrhosis)
picmonic thumbnail
picmonic thumbnail
Primary Sclerosing Cholangitis Mechanisms
picmonic thumbnail
Primary Sclerosing Cholangitis Labs and Treatment
picmonic thumbnail
Clonorchis Sinensis

Primary Biliary Cholangitis (Primary Biliary Cirrhosis) Diagnosis and Treatment

#1 Foam-finger Bile-duck and Cola-angel
Primary Biliary Cirrhosis (PBC) is an inflammatory autoimmune reaction leading to destruction of intrahepatic bile ducts. As bile ducts are destroyed, cholestasis results, and over time this may lead to cirrhosis and liver failure. Patients typically have antimitochondrial antibodies present, along with elevated serum alkaline phosphatase and increased cholesterol. Treatment includes ursodiol and liver transplant.
Positive Antimitochondrial Antibodies
Positive Anti-Mitochondrial-factory Ant-tie-body

95% of patients with PBC show increased serum antimitochondrial antibodies, which are the characteristic autoantibodies in this disease. These stimulate autoreactive T cells to accumulate around bile ducts and hepatocytes.

Increased Alkaline Phosphatase (ALK-P)
Up-arrow Elk-P

Studies will also show increased serum alkaline phosphatase (ALP or ALK-P), which is a marker of cholestasis.

Increased Cholesterol
Up-arrow Cholesterol-burger

In PBC, and other situations where cholestasis occurs, the ability to transport and breakdown cholesterol is impaired. This yields increased serum cholesterol.


This is the only FDA-approved medication to treat PBC, and works by reducing the rate of intestinal cholesterol absorption. It also works to nonsurgically treat gallstones, while limiting symptoms of cholestasis (jaundice, pruritis).

Liver Transplant
Liver Train-plant

The onset of this disease is insidious. It eventually leads to liver cirrhosis and an increased risk of hepatocellular carcinoma. Liver transplant is the best form of treatment in patients with end-stage liver disease.


Take the Primary Biliary Cholangitis (Primary Biliary Cirrhosis) Diagnosis and Treatment Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,820,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.