Ependymomas are common in children and present in the 4th ventricle.
The most common location for ependymomas in children is in the fourth ventricle. Because of this positioning, they can obstruct CSF outflow.
Ependymomas can present with hydrocephalus due to obstruction of CSF outflow, especially if the tumors are in the posterior fossa. This can present clinically as headache, nausea and vomiting.
This describes the rosette arrangement of cells around a blood vessel rather than a lumen. Perivascular pseudorosettes can be found in ependymomas.
Rod shaped blepharoplasts are also known as basal ciliary bodies. This is a feature of fully differentiated ependymal cells. Therefore, rod shaped blepharoplasts can be found in ependymomas.
While the fourth ventricle is the most common location for ependymomas in children, adults commonly present with ependymomas in the cauda equina region of the spinal canal.
Ependymomas can have a poor prognosis due to its ability to disseminate throughout the CSF.
Ependymomas can be seen in those with Neurofibromatosis type II. NFII is also known as MISME syndrome (Multiple Inherited Schwannomas, Meningiomas, and Ependymomas). It is an inherited disorder manifesting as non-malignant brain tumors.
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