Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
- Autonomic Instability
 - Muscle Rigidity
 - Ryanodine Receptor 1 Mutation
 - Inhaled Anesthetics
 - Succinylcholine
 - Dantrolene
 - Antidopaminergic Medications
 - Hyporeflexia
 - Myoglobinuria
 - Dantrolene
 - Serotonergic Medications
 - Hyperreflexia
 - Clonus
 - Cyproheptadine
 
Glasgow Coma Scale
- LOC Assessment
 - Score of 3 to 15
 - 8 or Less = Coma
 - Eye Opening
 - Verbal Response
 - Motor Response
 
Tardive Dyskinesia
- Bizarre Facial Movements
 - Bizarre Tongue Movement
 - Increased Extremity Movements
 - Stiff Neck
 - Dysphagia
 - Stop Medication
 - AIMS
 
Malignant Hyperthermia
- Autosomal-Dominant
 - Ryanodine Receptor 1 Mutation
 - Inhaled Anesthetics
 - Succinylcholine
 - Autonomic Instability
 - Muscle Rigidity
 - Dantrolene
 
Serotonin Syndrome Assessment
- Restlessness
 - Diaphoresis
 - Tachycardia
 - Hypertension
 - Diarrhea
 - Hyperthermia
 - Decreased Level of Consciousness
 - Muscle Rigidity
 - Seizure and Coma
 - Cyproheptadine
 
Chorea and Athetosis
- Sudden Jerky Movements
 - Athetosis
 - Snake-like, Writhing Movements
 - Basal Ganglia Lesions
 - Huntington's Disease
 - Acute Rheumatic Fever
 - Treat Underlying Disorder
 - Tetrabenazine
 
Ballismus and Hemiballismus
- Involuntary Flailing Movements
 - Worse with Activity; Improved with Rest
 - Basal Ganglia Dysfunction
 - Subthalamic Nucleus
 - Stroke
 - Diabetes
 - Infection
 - Neoplasm
 - Antidopaminergic Medications
 
Essential Tremor
- Most Common Tremor in Adults
 - Positive Family History
 - Bilateral Upper Extremities
 - Worse with Physical and Psychological Stress
 - Better with Rest and Alcohol
 - Beta Blockers
 - Primidone
 
Intention Tremor
- More Apparent With Goal-Directed Movements Such as Using Eating Utensils
 - High-Amplitude, Low-Frequency
 - More Apparent as Extremity Approaches Target
 - Overshooting and Undershooting
 - Ipsilateral Cerebellar Damage
 - Neurologic Exam
 - MRI
 - Physical or Occupational Therapy
 
Trigeminal Neuralgia (Tic Douloureux)
- Tic Douloureux
 - Cranial Nerve V - Trigeminal Nerve
 - Stabbing Unilateral Facial Pain
 - Facial Spasms
 - Psychological Disturbances
 - More Common in Women > 60 Years Old
 - Diagnosis by Clinical Impression
 - MRI
 - Carbamazepine
 - Surgery As Last Resort
 
Creutzfeldt-Jakob Disease (CJD)
- Misfolded Prion Protein
 - Spongiform Encephalopathy
 - Sporadic Type
 - Familial Type
 - Variant Type
 - Iatrogenic Type
 - Rapidly Progressive
 - Dementia
 - Ataxia
 - Myoclonus
 - Magnetic Resonance Imaging (MRI)
 - Increased Levels of 14-3-3 Protein
 - Periodic Sharp Waves On EEG
 - Supportive Care
 
Pseudotumor Cerebri: Diagnosis and Management
- Lumbar Puncture with Increased Opening Pressure
 - Normal MRI or CT
 - Weight Loss
 - Acetazolamide
 - Topiramate
 - Surgery
 - Avoid Triggers
 
Pseudotumor Cerebri: Risk Factors And Presentation
- Increased Intracranial Pressure With Unknown Etiology
 - Women of Childbearing Age
 - Obesity
 - Vitamin A Excess
 - Tetracyclines
 - Papilledema
 - Headache
 - Diplopia
 - Cranial Nerve VI (Abducens) Palsy
 - No Altered Mental Status
 
Hydrocephalus Types
- Cerebrospinal Fluid Accumulation
 - Communicating Hydrocephalus
 - Noncommunicating Hydrocephalus
 - Normal Pressure Hydrocephalus
 - Hydrocephalus Ex Vacuo
 
Sciatica
- Compression or Damage to Sciatic Nerve
 - Herniated Disc
 - Shooting Pain
 - Lower Back Down to Thigh
 - Anti-Inflammatories
 - Steroid Injections
 - IDET (Intradiscal Electrothermoplasty)
 - Straight-leg Raising Test
 
Adrenoleukodystrophy
- X-linked Recessive
 - Peroxisome Dysfunction
 - ABCD1 Mutation
 - Adrenal Insufficiency
 - Leukoencephalopathy
 - Testicular Insufficiency
 - Increased Very Long-chain Fatty Acids (VLCFA)
 - Demyelination
 - Genetic Testing
 - Lorenzo's Oil
 - Hematopoietic Stem Cell Transplantation
 
Refsum Disease
- Autosomal Recessive
 - Peroxisome Dysfunction
 - Increased Phytanic Acid
 - Retinitis Pigmentosa
 - Hearing Loss
 - Polyneuropathy
 - Anosmia
 - Ataxia
 - Genetic Testing
 - Dietary Changes
 - Plasmapheresis
 
Asterixis
- Flapping Tremor
 - Periodic Loss of Postural Muscle Tone with Arms in Extension
 - Corrective Movements
 - Hyperammonemia
 - Liver Disease
 - Hepatic Encephalopathy
 - Kidney Disease
 - Uremia
 - Treat Underlying Disorder
 
Tremor Types
- Resting Tremor
 - Postural Tremor
 - Essential Tremor
 - Physiologic Tremor (Reversible)
 - Intention Tremor
 - Asterixis (Flapping Tremor)
 
Cranial Nerve Pathologies
- Horner Syndrome
 - Trigeminal Neuralgia
 - Bell's Palsy
 - Brain or Brainstem Lesion
 - Microvascular Cranial Nerve Palsy
 - Glossopharyngeal Neuralgia
 - Multiple Sclerosis
 - Arnold Chiari Malformation
 - Amyotrophic Lateral Sclerosis (ALS)
 - Guillain Barre’ Syndrome
 - Parkinson's Disease
 
Lesions of the Brain and Presentations
- Frontal Lobe
 - Parietal Lobe
 - Temporal Lobe
 - Occipital Lobe
 - Brainstem
 - Cerebellum
 - Epidural Hematoma
 - Subdural Hematoma
 - Contusion/ Parenchymal Hemorrhage
 - Intraventricular Hematoma
 - Subarachnoid Hemorrhage
 - Diffuse Axonal Injury