Master Ehrlichiosis with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Ehrlichiosis

Ear-lick
Nicholazk
11 KEY FACTS
CHARACTERISTICS
Intracellular Gram-Negative Rod
Graham-cracker Negative-devil with Rod Inside Cell

Ehrlichia chaffeensis and E. ewingii are obligate intracellular gram-negative rods. They are zoonotic pathogens that are transmitted to humans by the lone star tick and are the causative agent of ehrlichiosis.

Lone Star Tick
Star-Tick

The lone star tick (Amblyomma Americanum) is indigenous to Mexico and the southeastern United States. This tick transmits human monocytic ehrlichiosis. 

Deer Reservoir
Deer

White-tailed deer is the major reservoir of Ehrlichia chaffeensis.

CLINICAL FEATURES
Fever
Fever-beaver

Immune response to Ehrlichia with resultant release of interleukins and cytokines leads to the development of fever in patients who are infected.

Flu-like Symptoms
Thermometer and Ice-bag

Inflammation triggerred by the infection often leads to non-specific flu-like symptoms (e.g., myalgias, fever).

Rash is Rare
Dermatologist Looking At a Rare Rash

Ehrlichiosis can mimic Rocky Mountain spotted fever (RMSF) in its clinical manifestations (e.g., fever, myalgias, pancytopenia). However, the rash is rare in ehrlichiosis, which is why it is sometimes referred to as "spotless RMSF".

DIAGNOSTIC WORKUP
Antibody Testing
Ant-tie-body with Test-Tubes

The diagnosis of ehrlichiosis is confirmed by antibody testing such as indirect immunofluorescence antibody (IFA) assay for immunoglobulin G (IgG).

Pancytopenia
Pan-side-toe-peanut

Pancytopenia is common in patients with ehrlichiosis. Thrombocytopenia and leukopenia are particularly common. Anemia is less common and is caused by the erythrocytic invasion by Ehrlichia.

Monocytes with Cytoplasmic Morulae
Monkey-monocyte-More-LA

Wright-Giemsa stain of the blood smear often reveals monocytes with cytoplasmic morulae. Morulae are cytoplasmic inclusions made up of microcolonies of Ehrlichia.

TREATMENT
Doxycycline
Dachshund-cycling

Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit and can be used for the treatment of ehrlichiosis.

Tetracycline
Tetris-cycle

Tetracyclines (e.g., doxycycline) are used for the treatment of ehrlichiosis. These antibiotics bind to the 30S prokaryotic ribosomal subunit in the mRNA translation complex. By doing so, these drugs prevent the binding of aminoacyl tRNA to the mRNA ribosome complex. The role of aminoacyl tRNA is to deliver the amino acid to the ribosome where it will be incorporated into the polypeptide chain that is being produced. Therefore, if the binding of aminoacyl tRNA subunit is inhibited, protein synthesis will be decreased.

Unlock all 11 facts & definitions with Picmonic Free!

JOIN FREE

Take the Ehrlichiosis Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 1,060,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medical (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.