Activated Charcoal (Actidose)
- Binds to Toxins
- Ingested Poison
- Black Stool
- GI Distress
- Give As Soon As Possible
- Via Mouth or NG Tube
- Gastric Lavage
- Do Not Administer with Antidotes
Acetaminophen
- Fever
- Pain
- Reversibly Inhibits COX
- Acts Primarily in CNS
- Hepatic Necrosis
- N-acetylcysteine Antidote
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Emesis
- Lacrimation
- Salivation
- Sweating
Acetylcholinesterase Inhibitor Antidote
Indirect Cholinomimetics
- Acetylcholinesterase Inhibitors
- Edrophonium
- Myasthenia Gravis (Diagnosis)
- Pyridostigmine and Neostigmine
- Myasthenia Gravis (Tx)
- Ileus
- Physostigmine
- Atropine Overdose
- Glaucoma
- Donepezil
- Alzheimer's
Atropine
- Blocks DUMBBeLSS
- Bradycardia
- Skin Flushing
- Increased Temperature
- Dry Mouth
- Cycloplegia
- Disorientation
- Mydriasis
Anticholinergics
- B.O.AT.S Acronym
- Benztropine
- Parkinson's Disease
- Oxybutynin
- Decrease bladder spasms
- Atropine
- Mydriasis and Cycloplegia
- Scopolamine
- Motion Sickness
Arsenic, Gold and Copper Antidotes
- Arsenic
- Gold
- Copper
- Penicillamine
- Dimercaprol (BAL)
- Succimer
Systemic Effects of Beta-Blockers
- Respiratory
- Bronchoconstriction
- Metabolic
- Decreased Insulin
- Decreased Glycolysis and Lipolysis
- Eye
- Reduces Intraocular Pressure
Barbiturates
- Barb- Drug Names
- Seizure Treatment
- Anesthesia Induction
- Increased Duration of Cl- Channel Opening
- Decrease Neuron Firing
- Sedation
- Cardiovascular and Respiratory Depression
- CNS Depression
- P450 inducer
Phenobarbital (Barbiturates)
- Barbiturate
- Seizures
- Ataxia
- Paradoxical Excitement
- Fatigue/Drowsiness
- Monitor Plasma Levels
- High Potential for Abuse
Benzodiazepine Intoxication Assessment
- Drowsiness
- Confusion
- Respiratory Depression
- Hypotension
- Coma
- Flumazenil (Romazicon)
Acute Digoxin Toxicity
- Hyperkalemia
- Cholinergic (Nausea, Vomiting, Diarrhea)
- Blurry Yellow Green Vision with Halo of Light
- Arrhythmia
- Bradycardia
- Prolonged PR interval
- Decreased QT
- Scooping on EKG
- T Wave Inversion
Digoxin Toxicity Treatment
- Activated Charcoal
- Slowly Normalize K+
- Digibind (Anti-Digoxin Fab)
- Magnesium Sulfate
- Lidocaine
- Cardiac Pacing
Iron (Ferrous Sulfate)
- Ferrous Salts
- Anemia
- GI Distress
- Nausea and Vomiting
- Dark Stools
- Take Between Meals
- Liquid can Stain Teeth
- Keep out of Reach from Children
- Caution with GI Disorders
- Avoid Antacids
Lead Antidotes
- Dimercaprol
- CaEDTA
- Succimer
Anion Gap Metabolic Acidosis
- Increased Anion Gap
- MUDPILES
- Methanol
- Uremia
- Diabetic Ketoacidosis (DKA)
- Propylene Glycol
- Isoniazid or Iron
- Lactic Acid
- Ethylene Glycol
- Salicylates
Aspirin Poisoning (Salicylism) Assessment
- Nausea and Vomiting
- Tinnitus
- Confusion
- Hyperventilation
- Respiratory Alkalosis
- Metabolic Acidosis
- Coma
- Hyperthermia
Tricyclic Antidepressant (TCA) Antidote
- Sodium Bicarbonate (NaHCO3)
Theophylline
- Asthma
- Inhibits Phosphodiesterase
- Increases cAMP
- Cardiotoxicity
- Neurotoxicity
- Blocks Adenosine Action
Alteplase
- Tissue Plasminogen Activator
- Thrombosis
- Bleeding
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Minimize Bleeding
- Monitor for Shock
- Aminocaproic Acid
Warfarin
- Interferes with Vitamin K-dependent Clotting Factors
- Extrinsic Pathway
- Bridge with Heparin
- Chronic Anticoagulation
- Bleeding
- Necrosis
- Cytochrome P450
- Pregnancy
- FFP + Vitamin K
Warfarin Antidotes
- Vitamin K
- Fresh Frozen Plasma
ACE Inhibitor Toxicity
- CAPTOPRIL Mnemonic
- Cough
- Angioedema
- Potassium Changes (Hyperkalemia)
- Taste Change
- Hypotension
- Pregnancy Changes
- Rash
- Increased Renin
- Lower Angiotensin II
Substance Use Disorder Assessment (Formerly Substance Abuse Assessment)
- Changes in Mood
- Poor Hygiene
- Odd Sleep Patterns
- Frequent Injuries
- Relationship or Job Difficulty
- Poor Performance
- Anorexia OR Weight Loss
- Social Isolation
- Financial Problems
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Euphoria
- Miosis
- CNS Depression
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Naloxone
Naloxone (Narcan)
- Competitive Opioid Receptor Antagonist
- Opioid Induced CNS Depression
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Repeated Dosing Often Required
Alcohol Use Disorder Assessment (Formerly Alcohol Abuse Assessment)
- CNS Depression
- Wernicke-Korsakoff Syndrome
- GI Distress
- Cardiomyopathy
- Pancreatitis
- Cirrhosis
- Immunosuppression
- Sexual Dysfunction
- Screening (Assessments)
Alcohol Use Disorder Interventions (Formerly Alcohol Abuse Interventions)
- Reduce Environmental Stimuli
- Antianxiety Medications
- Vitamin Supplements
- Seizure Precautions
- Suicide Precautions
- Fever
- Identify Support Systems
- Group Therapy
- Disulfiram
- Naltrexone
Cocaine Intoxication Assessment
- Euphoria
- Delusions
- Mydriasis
- Hallucinations
- Agitation
- Hypertension
- Arrhythmias
- Hyperthermia
- Seizures
- Nasal Septum Perforation
LSD Intoxication Assessment
- Psychosis
- Perceptual Distortion
- Visual Hallucinations
- Paranoia
- Depersonalization
- Anxiety
- Tachycardia
- Flashbacks
Amphetamines Intoxication Assessment
- Euphoria
- Insomnia
- Mydriasis
- Diaphoresis
- Hypertension
- Tachycardia
- Paranoia
- Anxiety
- Anorexia
- Seizures
Marijuana Intoxication Assessment
- Euphoria
- Slowed Reaction Time
- Conjunctival Injection
- Increased Appetite
- Anxiety
- Social Withdrawal
- Paranoid Delusions
Phencyclidine (PCP) Intoxication Assessment
- Violent Behavior
- Motor Issues
- Nystagmus
- Increased Pain Tolerance
- Tachycardia
- Delirium
- Seizures
- Psychosis
Cyanide Poisoning Diagnosis and Treatment
- Lactic Acidosis
- Elevated Venous PO2
- Check Carboxyhemoglobin
- Sodium Nitrate PLUS Sodium Thiosulfate
- Methemoglobinemia
- OR Hydroxocobalamin (First Line)
Cyanide Poisoning: Pathophysiology and Clinical Manifestation
- Inhibits Complex IV of Oxidative Phosphorylation
- Forces Cells Into Anaerobic Metabolism
- Exposure to Fire Fumes
- Industrial Exposure
- Headache and Confusion
- Arrhythmias
- "Cherry Red" Skin
- Almond Breath/Taste
- Acute Renal Failure
Ethanol Metabolism
- Zero Order Elimination
- Ethanol
- Alcohol Dehydrogenase
- Produces NADH
- Acetaldehyde
- Acetaldehyde Dehydrogenase
- Produces NADH
- Acetate
- Thiokinase
- Acetyl-CoA
- Fomepizole
- Disulfiram
MDMA (Ecstasy) Toxicity: Management
- Airway Management
- Management of Hypertension
- Benzodiazapines
- Nitroprusside
- Activated Charcoal if Within One Hour of Ingestion
- Ice Bath if Hyperthermic
- Cyproheptadine if Serotonin Syndrome
- Fluid Restriction for Hyponatremia
- Hypertonic Saline if Hyponatremia + Altered Mental Status
MDMA (Ecstasy) Toxicity: Mechanism and Clinical Findings
- Sympathomimetic
- Increases Release and Blocks Reuptake of Catecholamines
- Euphoria
- Increased Alertness
- Extreme Hyponatremia Leading to Altered Mental Status
- Acute Liver Injury
- Serotonin Syndrome
- Rhabdomyolysis
- Hypertensive Urgency/Emergency
- Arrhythmia
Substance Use Disorder
- 2 or More Symptoms For 1 year
- Tolerance
- Withdrawal Symptoms
- Cravings
- Using More Than Intended
- Inability to Cut Down
- Time-Consuming Substance Acquisition
- Impaired Functioning at Work
- Reduced Recreational Activities
- Dangerous Activities
- Continued Use