Thiamine (B1) deficiency can lead to beriberi and Wernicke-Korsakoff syndrome. Thiamine deficiency is more common in alcoholics and people from third-world countries solely eating polished rice.
Dry beriberi is characterized by symmetric polyneuritis affecting both sensory and motor components of the distal extremities, leading to symmetrical extremity muscle wasting.
Polyneuritis is a neurological disorder that occurs when multiple nerves throughout the body are damaged simultaneously. Polyneuritis is a key component of dry beriberi.
Symmetrical loss of muscle mass is commonly seen in dry beriberi.
Wet beriberi is the term used for thiamine deficiency with cardiovascular involvement.
Dilated cardiomyopathy is a condition in which the heart becomes weakened and enlarged and cannot pump blood efficiently throughout the body.
Edema is an abnormal accumulation of fluid beneath the skin or cavities of the body that produces swelling. Edema is a common manifestation of wet beriberi.
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