Master Ehlers-Danlos Syndrome Types with Picmonic for Medicine

Classical Type (formerly Types 1 and 2) features include fragile, velvety and hyperelastic skin as well as delayed wound healing and joint hypermobility. It involves a defect in Type V collagen, and is inherited in an autosomal dominant pattern.

Classical Type (formerly Types 1 and 2) features include fragile, velvety and hyperelastic skin as well as delayed wound healing and joint hypermobility. It involves a defect in Type V collagen, and is inherited in an autosomal dominant pattern.

Classical Type (formerly Types 1 and 2) features include fragile, velvety and hyperelastic skin as well as delayed wound healing and joint hypermobility. It involves a defect in Type V collagen, and is inherited in an autosomal dominant pattern.

Hypermobility Type (formerly Type 3) is the most common variant of EDS. Patients present with unstable and dislocatable joints.

Hyper mobility Type Ehlers-Dalos (formerly Type 3) is the most common variant of EDS.

Patients with type 3 Ehlers-Danlos syndrome develop the hypermobility variant of this disease. Here, the glycoprotein Tenascin-X, which is found in connective tissues, joints and muscles, is absent. Because of this, patients develop hypermobile joints, and are more prone to dislocations and subluxations.

In the hypermobility variant of Ehlers-Danlos syndrome, patients have less severe skin manifestations, and more frequent joint pathologies. The hallmarks of this type of disease are joint instability, characterized by dislocations and subluxations (with or without trauma), along with chronic musculoskeletal pain.

Vascular Type (formerly Type 4) is due to a defect in Type III collagen, and is characterized by translucent skin with visible vessels, vascular and organ rupture (i.e. vertebral artery dissection), and easy bruising.

The vascular variant of Ehlers-Danlos syndrome occurs when there is a defect in type-III collagen synthesis. Type-III collagen is an important protein that is found in extensible connective tissues, such as skin and the vascular system.

In this variant of Ehlers-Danlos syndrome, blood vessels and organs are fragile and prone to tearing, especially when an infection is present. These are important complications of this disease to be familiar with.