Medicine (MD/DO)
Fundamentals of Genetics
Hardy-Weinberg Principle

Master Hardy-Weinberg Principle with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Hardy-Weinberg Principle

Recommended Picmonics

picmonic thumbnail
Alport Syndrome
picmonic thumbnail
Fragile X
picmonic thumbnail
Cystic Fibrosis Mechanisms
picmonic thumbnail
Von Hippel-Lindau Disease
picmonic thumbnail
Marfan Syndrome

Hardy-Weinberg Principle

Hairy Wine-Burger
The Hardy-Weinberg Principle states that allele and genotype frequencies in an ideal population, one without evolutionary forces, will remain constant between generatinons. The evolutionary forces can be grouped into five conditions: no selection, a large population, no migration, random mating, and no net mutations. Any of these five conditions will cause a shift in allele or genotype frequency that will move a population out of Hardy-Weinberg equilibrium.
Constant Allele and Genotype frequencies with no evolutionary forces
A-Lily and Genie-Type on Crescent with Frequency unreachable by Evolutionary-Man

The Hardy-Weinberg Principle states that allele and genotype frequencies in an ideal population, one without evolutionary forces, will remain constant between generatinons.

Conditions for Equilibrium

The evolutionary forces can also be described as 5 conditions that need to be met for a population to be in Hardy-Weinberg equilibrium.

No selection
No Selection Sign at peeking Hairy Wine-Burger

One of the conditions is no selection. This means that there can be no selection against inferior traits or for beneficial traits in the population.This would cause a boon to the beneficial alleles and removal from Hardy-Weinberg equilibrium.

Large population
Large Pop

Small population sizes can result in deviations from Hardy-Weinberg equilibrium due to genetic drift. This occurs because the effects of random sampling are more prominent in a smaller population size. That is why large populations are needed for Hardy-Weinberg equilibrium.

No migration
Migratory-Geese being Blocked

If individuals are allowed to migrate from population to population, that can shift the allelic and genotypic frequencies over time.

Random mating
Blindfolded Kissing

Individuals must mate randomly to preserve Hardy-Weinberg equilibrium. If not, situations like inbreeding can occur which will cause an increase in homozygous phenotypes for all genes.

No net mutations
Net Mutant Not Allowed

Mutations can change the genotype and phenotype of an individual. No net mutations means that there can be some mutations, as long as they cancel each other out. For example, if a mutation causes A to change to B in one individual and another mutation causes B to change to A in a different individual, those two effects cancel out.


Take the Hardy-Weinberg Principle Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,890,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.