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Medicine (MD/DO)
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Biochemistry
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Fundamentals of Metabolism

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Biochemistry | Medicine (MD/DO) School Study Aid

Fundamentals of Metabolism
7 Picmonics to Learn | 12 mins
Aerobic Respiration
Mitochondrial Matrix
2 Pyruvate
Pyruvate Decarboxylation
2 NADH
2 Acetyl-CoA
Krebs Cycle
6 NADH
2 FADH2
2 Substrate Level ATPs
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1 min
Anaerobic Respiration
Cytosol
Glucose
Glycolysis
Substrate-level Phosphorylation
2 NADH
2 Net ATP
2 Pyruvate
Fermentation
NAD+ Regeneration
Waste Byproduct
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2 mins
Oxidative Phosphorylation
Inner Mitochondrial Membrane
Electron Transport Chain
Oxygen is Final Electron Acceptor
Proton Pump
Proton Motive Force
ATP Synthase
1 NADH 2.5 ATP
1 FADH2 1.5 ATP
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3 mins
Energy Releasing Pathways: Accounting
Characteristics
Anaerobic Respiration
2 ATP
2 NADH
Aerobic Respiration
8 NADH
2 FADH2
2 ATP
Oxidative Phosphorylation
34 ATP
2 ATP Lost
36 Net Total ATP
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2 mins
Enzyme Types
Characteristics
Lyases
Hydrolases
Transferases
Isomerases
Oxidoreductases
Ligases
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1 min
Competitive Inhibition
Reversible Inhibition
Constant Vmax
Substrate Competes With Inhibitor For The Active Site
Inhibition Increases Km
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1 min
Non-Competitive Inhibition
Characteristics
Reversible Inhibition
Substrate Freely Binds The Active Site
Inhibitor Strongly Binds Allosteric Site
Km Constant
Enzyme Has Different Conformational Form
Low Vmax
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2 mins

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