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Immunodermatologic Disorders

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Pathology | Physician Assistant (PA) School Study Aid

Immunodermatologic Disorders
11 Picmonics to Learn | 21 mins
Atopic Dermatitis / Eczema
Presentation
Pruritic Vesicles
Inflammatory Skin Rash
Cheeks in Children
Skin Flexural Areas
Associated with Asthma and Allergic Rhinitis
Treatment
Tacrolimus
Moisturizers
Corticosteroids
Phototherapy
Avoid Triggers
Antihistamines
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2 mins
Vitiligo
Pathophysiology
Autoimmune Destruction of Melanocytes
Presentation
Hypopigmentation
Acral Areas and Around Orifices
Diagnosis
Clinical Presentation + Woods Lamp
Risk Factors
Other Autoimmune Diseases
Treatment
Glucocorticoids
Tacrolimus
Phototherapy
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2 mins
Psoriasis
Presentation
Epidermal Hyperproliferation Keratinocytes
Defined Red Salmon Plaques
Silvery Scales
Extensor Surfaces
Bleeding when Removed
Auspitz Sign
Pruritus
Nail Changes
Histological Finding
Munro Microabscesses
Nucleated Cells in Stratum Corneum
Treatment
Retinoids
Topical Corticosteroids
Tar
Immunosuppressants
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2 mins
Lichen Planus
Pathophysiology
Mucocutaneous Disorder
30-60 year olds
Signs & Symptoms
Pruritic
Plaques or Papules
Purple & Polygonal
Often Mucosal or Genital Involvement
Wickham Striae
Diagnosis
Biopsy
Sawtooth Infiltrate of Lymphocytes
Treatment
Topical Corticosteroids
Considerations
Hepatitis C Association
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2 mins
Erythema Nodosum
Pathophysiology
Panniculitis
Painful Inflammation
Subcutaneous Fat
Anterior Shins
Risk Factors
Coccidioidomycosis
Pregnancy or OCP Use
Crohn's Disease
Tuberculosis (TB)
Histoplasmosis
Sarcoidosis
Ulcerative Colitis
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2 mins
Pemphigus Vulgaris
Pathophysiology
Autoantibodies against desmosomes
Symptoms
Flaccid Bullae on Skin
Oral Mucosa Involvement
Intraepidermal Acantholysis
Fluid Loss
Infection
Nikolsky Positive
Diagnosis
Biopsy showing Autoantibodies
Treatment
IVIG and Plasmapheresis
Oral Steroids
Immunosuppressants
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2 mins
Anti-desmoglein Antibodies
Pemphigus Vulgaris
Flaccid Blisters
Skin and Oral Mucosa
Positive Nikolsky's Sign
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59 secs
Bullous Pemphigoid
Linear Deposits of IgG
Affects Hemidesmosomes
Epidermal Basement Membrane
Tense Blisters on Skin
Nikolsky Negative
Contain Eosinophils
Rarely Affect Oral Mucosa
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2 mins
Rosacea
Characteristics
Episodes Provoked by Alcohol, Heat, or Emotions
Erythematotelangiectatic Rosacea
Facial Flushing and Telangiectasias
Sun Protection
Topical Brimonidine
Papulopustular Rosacea
Papules and Pustules
Topical Metronidazole
Phymatous Rosacea
Rhinophyma
Laser Ablation
Considerations
Avoid Triggers
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2 mins
Raynaud Phenomenon Characteristics and Presentation
Characteristics
Stress-induced Vasospasm
Primary Type
Primary Raynaud Phenomenon
Idiopathic
Reversible
Symmetric
Secondary Type
Secondary Raynaud Phenomenon
Autoimmune Diseases
Drugs
Severe Pain
Presentation
Ischemic Phase
Hypoxic Phase
Hyperemic Phase
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2 mins
Raynaud Phenomenon Diagnosis and Management
Diagnosis
Nailfold Capillary Microscopy
Complete Blood Count (CBC)
Antibody Testing
Management
Avoid Triggers
Smoking Cessation
Nifedipine
Topical Nitroglycerin
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2 mins

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