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Pathology | Physician Assistant (PA) School Study Aid
Respiratory Alkalosis
- Hyperventilation
- High Altitude
- Aspirin
- Restrictive Lung Disease
- Pulmonary Embolism
- Pregnancy
- Progesterone
- Rib Fracture
- Anxiety
2 mins
Respiratory Alkalosis Interventions
- Treat Underlying Cause
- Mechanically Ventilated Patients
- Decrease Tidal Volume and/or Respiratory Rate
- Give Adequate Pain Control and Sedation
- Hyperventilation Syndrome
- Sedatives
- Antidepressants
- Considerations
- Compensatory Drop in Serum Bicarbonate
- Calming Breathing Exercises
- Correct CO2 Slowly
2 mins
Respiratory Acidosis
- Hypoventilation
- Increased PaCO2 > 45
- Barbiturates Depress Central Respiratory Center of Brain
- Opioids Depress Central Respiratory Center of the Brain
- Airway Obstruction
- Respiratory Muscle Weakness/Paralysis
3 mins
Respiratory Acidosis Interventions
- Improve Respiration
- Pharmacologic Interventions
- Bronchodilators
- Respiratory Stimulants
- Drug Antagonists
- Nonpharmacologic Interventions
- Oxygen
- Assisted Ventilation
- Prevent Complications
1 min
Metabolic Alkalosis
- Diuretic use
- Vomiting
- Antacid
- Hyperaldosteronism
26 secs
Metabolic Alkalosis Interventions
- Interventions
- Treat Underlying Cause
- Stop Potassium (K+) Wasting Diuretics
- Spironolactone
- Acetazolamide
- IV Fluids
- Sodium Chloride
- Replace Potassium (K+)
- Considerations
- Monitor Respiratory Rate
- Monitor Heart Rate
- Seizure Precautions
2 mins
Normal Gap Metabolic Acidosis
- HARD-ASS
- Hyperalimentation
- Addison's Disease
- Renal Tubular Acidosis
- Diarrhea
- Acetazolamide
- Spironolactone
- Saline Infusion
2 mins
Anion Gap Metabolic Acidosis
- Pathophysiology
- Increased Anion Gap
- MUDPILES
- Methanol
- Uremia
- Diabetic Ketoacidosis (DKA)
- Propylene Glycol
- Isoniazid or Iron
- Lactic Acid
- Ethylene Glycol
- Salicylates
1 min
Metabolic Acidosis Interventions
- Interventions
- Raise Plasma pH > 7.20
- Treat Underlying Cause
- Sodium Bicarbonate
- Considerations
- Follow ABGs
- Continuously Monitor Patient
2 mins
Fanconi Syndrome Characteristics
- Pathophysiology
- Resorption Defect in Proximal Tubule
- Signs and Symptoms
- Hypophosphatemia
- Rickets
- Osteomalacia
- Hypokalemia
- Metabolic Acidosis
- Type 2 Renal Tubular Acidosis
- Treatment
- Treat Underlying Disorder
- Bicarbonate
1 min
Fanconi Syndrome Causes
- Hereditary Causes
- Cystinosis
- Dent's Disease
- Wilson's Disease
- Oculocerebrorenal (Lowe) Syndrome
- Galactosemia
- Hereditary Fructose Intolerance
- Glycogen Storage Diseases
- Tyrosinemia
- Acquired and Medication Causes
- Tenofovir
- Heavy Metals
- Expired Tetracyclines
- Cisplatin
- Gentamycin (Aminoglycosides)
- Valproate Sodium
- Multiple Myeloma
2 mins
Distal Renal Tubular Acidosis (Type I)
- Pathophysiology
- Distal Tube
- Defect in H+ Secretion
- Labs
- Increased Urinary pH
- Urinary pH >5.5
- Hypokalemia
- Causes
- Amphotericin B Toxicity
- Autoimmune Disease
- Lithium
- Obstruction Of The Urinary Tract
- Complication
- Kidney Stones
- Treatment
- Bicarbonate
3 mins
Type 2 Renal Tubular Acidosis
- Proximal Tubule
- Pathophysiology
- Inability To Reabsorb Bicarbonate
- ETIOLOGY
- Fanconi Syndrome
- Sporadic Type
- Familial Types
- Autosomal Recessive
- Acetazolamide
- Characteristics
- Decreased Urinary pH
- Hypokalemia
- Treatments
- Treat Underlying Disorder
- Alkali Therapy
4 mins
Renal Tubular Acidosis Type 4
- Characteristics
- Aldosterone Resistance
- Decreased Aldosterone Production
- Causes Of Hypoaldosteronism
- Addison’s Disease (Primary Adrenal Insufficiency)
- Hyporeninism
- Causes Of Aldosterone Resistance
- Trimethoprim-Sulfamethoxazole
- Potassium Sparing Diuretics
- Labs
- Hyperkalemia
- Low Urine pH
- Diminished Ammonium (NH4) Urinary Excretion
- Treatment
- Furosemide
- Fludrocortisone
5 mins
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