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First Aid for the USMLE Step 1 (2021)
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Page 361 -

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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid

Page 361 -
7 Picmonics to Learn | 17 mins
Insulinoma
Characteristics
Pancreatic Neuroendocrine Tumor
Benign
Associated with MEN-1
Clinical Features
Whipple Triad
Symptoms of Hypoglycemia
Hypoglycemia During Episode
Relief with Glucose
Diagnosis
Increased C-peptide
Management
Surgery
Octreotide
Diazoxide
picmonic thumbnail
2 mins
Glucagonoma
Characteristics
Pancreatic Neuroendocine Tumor
Originates from A Cells
Clinical Features
Weight Loss
Necrolytic Migratory Erythema
Depression
Diarrhea
Deep Vein Thrombosis
Diabetes Mellitus
Diagnosis
Increased Glucagon
Abdominal CT
Management
Octreotide
Surgical Resection
picmonic thumbnail
2 mins
Somatostatinoma
Characteristics
Pancreatic Neuroendocrine Tumor
Originates from Delta Cells
Clinical Features
Steatorrhea
Gallstones
Hyperglycemia
Diagnosis
Increased Somatostatin
Abdominal CT or MRI
Management
Octreotide
Surgical Resection
Chemotherapy
picmonic thumbnail
2 mins
Bronchial Carcinoid Tumor
Characteristics
Excellent Prognosis
Signs and Symptoms
Symptoms of Bronchial Obstruction
Often Asymptomatic
Carcinoid Syndrome
Diarrhea
Wheezing
Flushing
Diagnosis
5-HIAA in Urine
Nests of Neuroendocrine Cells
Chromogranin A Positive
Treatment
Surgical Resection
Octreotide for Symptomatic Relief
picmonic thumbnail
2 mins
Carcinoid Syndrome
Pathophysiology
Neuroendocrine Cells
Serotonin
Appendix
Diagnosis
Chromogranin A
Neuron Specific Enolase
Dense Core Bodies on EM
Signs and Symptoms
Symptoms When Metastasize to Liver
Flushing
Wheezing
Right Heart Murmur
Diarrhea
picmonic thumbnail
4 mins
Zollinger-Ellison Syndrome Disease
Pathophysiology
Gastrin-Secreting Tumor
Increased Gastric Acid
Recurrent Peptic Ulcers
MEN Type 1
Symptoms
Abdominal Pain
Heartburn (Pyrosis)
Diarrhea
picmonic thumbnail
3 mins
Zollinger-Ellison Syndrome Diagnosis and Treatment
Diagnosis
Gastrin > 1000 pg/mL
Positive Secretin Stimulation Test
Treatment
High-Dose PPI
Octreotide
Surgical Resection
picmonic thumbnail
3 mins

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