Insulinoma
- Pancreatic Neuroendocrine Tumor
- Benign
- Associated with MEN-1
- Whipple Triad
- Symptoms of Hypoglycemia
- Hypoglycemia During Episode
- Relief with Glucose
- Increased C-peptide
- Surgery
- Octreotide
- Diazoxide
Glucagonoma
- Pancreatic Neuroendocine Tumor
- Originates from A Cells
- Weight Loss
- Necrolytic Migratory Erythema
- Depression
- Diarrhea
- Deep Vein Thrombosis
- Diabetes Mellitus
- Increased Glucagon
- Abdominal CT
- Octreotide
- Surgical Resection
Somatostatinoma
- Pancreatic Neuroendocrine Tumor
- Originates from Delta Cells
- Steatorrhea
- Gallstones
- Hyperglycemia
- Increased Somatostatin
- Abdominal CT or MRI
- Octreotide
- Surgical Resection
- Chemotherapy
Bronchial Carcinoid Tumor
- Excellent Prognosis
- Symptoms of Bronchial Obstruction
- Often Asymptomatic
- Carcinoid Syndrome
- Diarrhea
- Wheezing
- Flushing
- 5-HIAA in Urine
- Nests of Neuroendocrine Cells
- Chromogranin A Positive
- Surgical Resection
- Octreotide for Symptomatic Relief
Carcinoid Syndrome
- Neuroendocrine Cells
- Serotonin
- Appendix
- Chromogranin A
- Neuron Specific Enolase
- Dense Core Bodies on EM
- Symptoms When Metastasize to Liver
- Flushing
- Wheezing
- Right Heart Murmur
- Diarrhea
Zollinger-Ellison Syndrome Disease
- Gastrin-Secreting Tumor
- Increased Gastric Acid
- Recurrent Peptic Ulcers
- MEN Type 1
- Abdominal Pain
- Heartburn (Pyrosis)
- Diarrhea
Zollinger-Ellison Syndrome Diagnosis and Treatment
- Gastrin > 1000 pg/mL
- Positive Secretin Stimulation Test
- High-Dose PPI
- Octreotide
- Surgical Resection