Ace Your First Aid for the USMLE Step 1 (2021) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Physician Assistant (PA) Students
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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid
Linezolid (Zyvox)
- Mechanism Of Action
- Oxazolidinone Antibiotic
- Binds 23S rRNA of 50S Subunit
- Inhibits Protein Synthesis
- Indication
- Gram-Positive Organisms
- MRSA
- VRE (Vancomycin Resistant Enterococci)
- Side Effects
- Bone Marrow Suppression
- Decreased Platelet Count
- Peripheral Neuropathy
- Lactic Acidosis
- Serotonin Syndrome
- Considerations & Patient Education
- Avoid Tyramine Containing Foods
4 mins
Macrolides
- Bacteriostatic
- Erythromycin
- Azithromycin
- Clarithromycin
- Bind to 23S rRNA of 50S subunit
- Inhibit protein synthesis by blocking translocation
- Gram-Positive Cocci
- Atypical pneumonia
- Chlamydia
- Resistance by methylation of 23S rRNA binding
1 min
Macrolides Side Effects
- Side Effects
- Diarrhea
- Prolonged QT Interval
- P450 Inhibitor
- Cholestatic Hepatitis
- Skin Rash
- Eosinophilia
3 mins
Polymyxins
- Mechanism of Action
- Cationic
- Act Like Detergents
- Bind to Cell Membranes of Bacteria
- Disrupt Their Osmotic Properties
- Indications
- Resistant Gram-Negative Infections
- Side Effects
- Neurotoxicity
- Renal tubular necrosis
3 mins
