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Physician Assistant (PA)
First Aid for the USMLE Step 1 (2021)
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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid

Page 691 -
3 Picmonics to Learn | 9 mins
Cyanide Poisoning: Pathophysiology and Clinical Manifestation
Inhibits Complex IV of Oxidative Phosphorylation
Forces Cells Into Anaerobic Metabolism
Exposure to Fire Fumes
Industrial Exposure
Headache and Confusion
"Cherry Red" Skin
Almond Breath/Taste
Acute Renal Failure
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4 mins
Cyanide Poisoning Diagnosis and Treatment
Lab Findings
Lactic Acidosis
Elevated Venous PO2
Check Carboxyhemoglobin
Sodium Nitrate PLUS Sodium Thiosulfate
OR Hydroxocobalamin (First Line)
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4 mins
Mechanism of Action
Direct Release of NO
Increase cGMP
Short Half-Life
Malignant Hypertension
Side Effect
Cyanide Toxicity
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1 min

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