Ace Your First Aid for the USMLE Step 1 (2021) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Physician Assistant (PA) Students
With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing. Whether you're studying for your classes or getting ready for a big exam, we're here to help.
First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid
Erlotinib
- Mechanism of Action
- Inhibits EGFR Tyrosine Kinase
- Inhibits Progression of G1 to S Phase
- Indications
- Non-small Cell Lung Cancer (NSCLC)
- Pancreatic Cancer
- Side Effects
- Rash
- Diarrhea
- Considerations
- Avoid Grapefruit Juice
1 min
Imatinib (Gleevec)
- Indications
- Chronic Myelogenous Leukemia (CML)
- Inhibitor of BCR-ABL Tyrosine Kinase
- Caused by Philadelphia Chromosome
- GI Stromal Tumors
- Inhibitor of C-kit Tyrosine Kinase
- Toxicity
- Fluid Retention
1 min
Primary Myelofibrosis
- Characteristics
- Bone Marrow Fibrosis
- Extramedullary Hematopoiesis
- JAK2 Kinase Mutation
- Symptoms
- Fatigue
- Weight Loss
- Splenomegaly
- DIagnosis
- Pancytopenia
- Dacrocytes (Teardrop Cells)
- Dry Tap on Bone Marrow Aspiration
- Treatment
- Stem Cell Transplantation
- Transfusion
- Ruxolitinib (JAK2 Inhibitor)
2 mins
BRAF Inhibitors
- Characteristics
- BRAF Proto-oncogene
- Serine/Threonine Kinase
- V600E Mutation
- Indications
- Melanoma
- Non-Hodgkin Lymphoma
- Papillary Thyroid Carcinoma
- Hairy Cell Leukemia
- Drugs
- Dabrafenib
- Vemurafenib
2 mins
Fluorouracil (5-FU)
- Mechanism
- Antimetabolite
- "Thymine-less Death"
- Indications
- Slow-growing Solid Tumors
- Co-administered with Leucovorin for Stomach Cancer
- Basal Cell Carcinoma (Topical)
- Side Effects
- Myelosuppression
- Mucositis
- Severe Diarrhea
3 mins
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Trimethoprim
- Mechanism of Action
- Bacteriostatic
- Inhibits Bacterial Dihydrofolate Reductase
- Causes Sequential Block of Folate Synthesis
- Used in Combination with Sulfamethoxazole
- Combination Used For Recurrent Urinary Tract Infections
- Indications
- Shigella
- Salmonella
- Pneumocystis Jiroveci Pneumonia
- Side Effects
- Decrease in Red and White Blood Cells
- Alleviated with Leucovorin Rescue
2 mins
Rasburicase
- Characteristics
- Recombinant Uricase
- Converts Uric Acid to Allantoin
- Inidication
- Hyperuricemia
- Tumor Lysis Syndrome
- Side Effects
- Hypersensitivity Reaction
- Methemoglobinemia
- Considerations
- Contraindicated in G6PD Deficiency
1 min
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Metoclopramide
- Indications
- Antiemetic
- Promotility Agent
- Mechanism
- Increased Resting Tone
- Antagonist at D2 Receptor
- Side Effects
- Parkinsonian Symptoms
- Galactorrhea
- Contraindication
- Small Bowel Obstruction
- Parkinson's Disease
2 mins
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
