Rituximab
- Chronic Lymphocytic Leukemia (CLL)
- Non-Hodgkin Lymphoma
- Rheumatoid Arthritis
- Microscopic Polyangiitis (MPA)
- Wegener's (Granulomatosis with Polyangiitis)
- Monoclonal Antibody Against CD20
- Found on B Cell Neoplasms
- Infusion Reactions
- Skin and Mouth Reactions
- Reactivation of Hepatitis B Virus (HBV)
- Progressive Multifocal Leukoencephalopathy (PML)
Bevacizumab Mechanisms and Indications
- Monoclonal Antibody to VEGF
- Inhibits Angiogenesis (and Vasculogenesis)
- Capillaries Grow CORN (CG-CORN acronym)
- Colorectal Cancer
- Glioblastoma
- Cervical Cancer
- Ovarian Cancer
- Renal Cell Carcinoma
- Non-small Cell Lung Cancer (NSCLC)
- Age-related Macular Degeneration
Bevacizumab Side Effects
- Impaired (Delayed) Wound Healing
- Hemorrhage
- Nosebleed (Epistaxis)
- GI Perforation
- Thromboembolic Event
- Osteonecrosis of the Jaw
Hypercalcemia Treatments
- Treat Underlying Disorder
- Hydration
- Dialysis
- Calcium Restriction
- Bisphosphonates
- Calcitonin
- Cinacalcet
- Glucocorticosteroids
- Denosumab
Celecoxib
- Rheumatoid Arthritis
- Osteoarthritis
- Pain
- NSAID
- Selectively Inhibits COX-2
- Sulfa Allergy
- Increased Risk of Thrombosis
- GI Bleed
- Pregnancy > 30 Weeks
BRAF Inhibitors
- BRAF Proto-oncogene
- Serine/Threonine Kinase
- V600E Mutation
- Melanoma
- Non-Hodgkin Lymphoma
- Papillary Thyroid Carcinoma
- Hairy Cell Leukemia
- Dabrafenib
- Vemurafenib
Imatinib (Gleevec)
- Chronic Myelogenous Leukemia (CML)
- Inhibitor of BCR-ABL Tyrosine Kinase
- Caused by Philadelphia Chromosome
- GI Stromal Tumors
- Inhibitor of C-kit Tyrosine Kinase
- Fluid Retention
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
Systemic Juvenile Idiopathic Arthritis Diagnosis and Management
- Increased Ferritin
- Glucocorticoids
- Tocilizumab
- Anakinra
- Joint Deformities
- Limb-Length Discrepancy
- Uveitis
- Macrophage Activation Syndrome
- Variable Prognosis