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Pharmacological Nursing Nursing (RN) School Study Aid


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Integumentary Pharmacology
9 Picmonics to Learn | 12 mins

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Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
Mechanism
Topical Antimicrobial
Indications
Burns
Open Wound Care
Side Effects
Mafenide
Pain
Acidosis
Considerations
Administer Analgesic Prior to Wound Care
1 min
Azoles (Ketoconazole)
"-azole" suffix
Indications
Local and Less Serious Systemic Mycosis
Mechanism
Inhibits Ergosterol Synthesis
Inhibits P450
Side Effects
Liver Dysfunction
Inhibition of Testosterone Synthesis
1 min
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
1 min
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
1 min
Flucytosine
Indications
Cryptococcus
Candida
Used in Combination with Amphotericin B or Azoles
Mechanism
Inhibits DNA and RNA Synthesis
Converted to 5-FU by Cytosine Deaminase
Side Effects
Bone Marrow Suppression
1 min
Griseofulvin
Mechanism
Disrupts Microtubules in Mitosis
Indications
Antifungal for Superficial Infections
Tinea and Ringworm
Side Effects
Teratogen
P450 Inducer
Confusion
Headache
1 min
Terbinafine
Indications
Dermatophytosis
Onychomycosis
Mechanism
Inhibits Squalene Epoxidase
Side Effects
Hepatotoxicity
GI Distress
Taste Disturbances
Headache
1 min
Echinocandins
"-Fungin" suffix
Indications
Invasive Aspergillosis
Candida
Mechanism
Inhibits Cell Wall Synthesis
Inhibits Synthesis of Beta-glucan
Side Effects
GI Distress
Flushing
1 min
Nystatin
Indications
Candidiasis
Vaginal
Oral
Cutaneous
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
Topical form of Amphotericin B
Side Effects
Rash
1 min

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