Lab values indicative of kidney function, such as BUN and creatinine, should be monitored closely in patients taking tacrolimus, as this medication can cause severe kidney damage.
Patients taking tacrolimus may experience symptoms of neurotoxicity including headache, tremor, and insomnia. Patients should not drink grapefruit juice while taking this medication, as it prevents the drug from being metabolized and can lead to toxicity.
Patients taking this medication may experience GI distress including, but not limited to diarrhea, nausea, and vomiting.
Suppression of the immune system increases a patient’s risk of developing an infection. Early signs of infection, such as a fever, should be reported to a healthcare professional immediately.
Increased blood pressure or hypertension may occur in patients taking tacrolimus. This condition can be treated with antihypertensive medication.
Tacrolimus can cause retention of potassium, which can lead to hyperkalemia. For this reason, patients taking this medication should avoid foods high in potassium.
Patients taking tacrolimus may experience increased blood glucose levels, as this medication can interfere with insulin secretion in the body.
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