In patients with metabolic syndrome, HDL levels are lower than normal, and triglyceride levels are elevated above 150 mg/dL.
Central obesity is defined as a male waist greater than 40 inches in diameter, or a female waist greater than 35 inches in diameter. Central obesity contributes to a diagnosis of metabolic syndrome.
Insulin resistance, related to excessive abdominal fat, may be present in patients with metabolic syndrome. A fasting glucose of 100 mg/dL or higher is indicative of insulin resistance.
Patients are considered hypertensive when systolic blood pressure is greater than 130 mmHg, or when diastolic blood pressure is greater than 85 mmHg.
C-reactive protein levels are typically elevated in patients with metabolic syndrome. The body is in a proinflammatory state, due to the increased release of inflammatory cytokines by excess fat tissue in the body.
Fibrinogen is necessary for blood clot formation; however, when levels of fibrinogen are increased, the patient is said to be in a prothrombotic state. Fibrinogen levels are typically elevated in patients with metabolic syndrome, due to the increased release of inflammatory cytokines by excess fat tissue in the body.
Metabolic syndrome is a combination of disorders that increases a patient’s overall risk of cardiovascular disease.
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