Maternity and Women's Health Care, 11th Ed., Lowerdermilk, Perry, Cashion & Aldon, 2016 |  Registered Nurse (RN) School Study Aid
Graves' Disease Characteristics
- Women 20-40 years old
 - Anti-TSH Receptor Antibodies
 - Ophthalmopathy
 - Exophthalmos
 - Hyperthyroidism
 - Goiter
 - Pretibial Myxedema
 
Graves' Disease Labs and Treatment
- Decreased TSH
 - Increased T3
 - Increased T4
 - Radioactive Iodine Uptake (RAIU)
 - Beta blocker
 - Methimazole
 - Radioiodine Ablation
 
Transdermal Medication Administration
- Patch or Disc
 - Directly on Skin of Arms, Chest, Upper Back
 - Avoids First Pass Metabolism
 - Sustained Administration of Medication
 - Clean Skin After Removal
 - Rotate Sites of Patches
 - Apply to Dry Skin
 - Avoid Shaved Skin
 - Avoid Heat
 - Nitro Effects Lost After 24 Hours
 
Metformin (Glucophage)
- Decrease Glucose Production
 - Increase Insulin Sensitivity
 - Type 2 Diabetes
 - Polycystic Ovary Syndrome (PCOS)
 - GI Distress
 - Decreased Appetite
 - Lactic Acidosis
 - IV Contrast
 - Limit Alcohol Consumption
 
Diabetes Assessment
- Juvenile Onset
 - Absent Insulin Production
 - Ketosis Prone
 - Adult Onset
 - Insulin Resistance
 - Obesity
 - Onset During Pregnancy
 - Glucose Intolerance
 - Retinopathy
 - Peripheral Vascular Disease
 - Nephropathy
 - Neuropathy
 
Pregnant Diabetic Patient Interventions
- Increase Insulin then Decrease
 - Metformin
 - Nutrition
 - Exercise
 - Increase Insulin
 - More Likely to Develop Hypoglycemia than Hyperglycemia
 - Double or Quadruple Insulin
 - Early Delivery
 - Drastically Decrease Insulin
 - Monitor Neonate for Hypoglycemia
 
Hyperglycemia
- Insulin Resistance
 - Too Little Insulin/Medication
 - Infection/Illness
 - Corticosteroids
 - Elevated Blood Glucose
 - Polyphagia
 - Polydipsia
 - Polyuria
 - Hypotension
 - Fatigue/Drowsiness
 
Hypoglycemia Intervention
- Mild to Moderate Hypoglycemia
 - Simple Carbohydrate (Oral Dextrose, Fruit Juice, Candies)
 - Complex Carbohydrate (Whole Grains, Vegetables)
 - Severe Hypoglycemia or Unconscious
 - 50% Dextrose
 - Glucagon
 - Monitor Blood Glucose Q 10-15 Minutes
 - Give Small Meal After Intervention
 - Hypoglycemia Prevention
 - Encourage Self-Monitoring
 
Hypoglycemia  Assessment
- Too much insulin
 - Decreased glucose
 - < 70 mg/dL
 - Change in LOC
 - Lethargic
 - Confusion and Irritability
 - Tremors
 - Diaphoresis
 - Tachycardia
 - Vision Changes
 - Weakness
 - Seizures
 
Diabetes Interventions
- Early Diagnosis
 - Insulin
 - Oral Hypoglycemics
 - Glucose Monitoring
 - Routine Exercise
 - Diabetic Diet
 - Monitor for Complications
 - Insulin Therapy
 - Diabetic Ketoacidosis (DKA)
 
Mixing NPH and Regular Insulin for Injection
- Verify Order
 - Roll NPH Insulin
 - Alcohol to Multiuse Vials
 - Inject Air into NPH Insulin (Cloudy)
 - Inject Air into Regular Insulin (Clear)
 - Withdraw Regular Insulin Units
 - Withdraw NPH Units
 - Verify with 2nd Nurse
 - Discard if Error
 
Insulin
- Rapid Acting
 - Insulin Lispro (Humalog)
 - Insulin Aspart (Novolog)
 - Insulin Glulisine (Apidra)
 - Short Acting 
 - Regular Insulin (Humulin R)
 - Intermediate Acting
 - Isophane NPH (Humulin N)
 - Long Acting
 - Detemir (Levemir)
 - Glargine (Lantus)
 
Diabetes Education
- Self-Monitoring (Blood Glucose)
 - SubQ Injection Technique
 - Lifestyle Changes
 - Symptoms of Hyperglycemia and Hypoglycemia
 - Sick Day Care
 - Foot Care
 - Exercise Therapy
 - Medication
 
Glucagon (GlucaGen)
- Increases Glucose
 - Hypoglycemic Emergency
 - Nausea and Vomiting
 - Reconstitute Powder
 - Consume Oral Carbohydrates
 - 50% Dextrose IV (If No Effect)
 
Oral Glucose Tolerance Test (OGTT)
- Used for Diabetes Screening
 - Fasting State
 - Baseline
 - Normal < 100 mg/dL
 - 30 and 60 Minutes
 - Normal < 200 mg/dL
 - 120 Minutes
 - Normal < 140 mg/dL
 
Glyburide and Glipizide (2nd Generation Sulfonylureas)
- 2nd Generation Sulfonylureas
 - Blocks Potassium Channels in Beta Cells
 - Stimulate Release of Insulin
 - Type 2 Diabetes
 - Hypoglycemia
 - More Potent
 - Beta Blockers Reduce Effects
 - Avoid Alcohol
 - Avoid Breastfeeding
 
Hyperemesis Gravidarum
- Excessive Vomiting
 - Significant Weight Loss
 - Dehydration
 - Hypotension
 - Electrolyte Imbalance
 - Antiemetics
 - Frequent Small Meals
 - IV Therapy
 
Chlorpromazine (Thorazine)
- Low Potency Antipsychotic
 - Schizophrenia
 - Hiccups
 - Sedation
 - Weight Gain
 - Orthostatic Hypotension
 - Anticholinergic Effects
 - QT Prolongation
 - Neuroendocrine Effects
 - Caution in Seizure Patients
 - Corneal Deposits
 
Promethazine (Phenergan)
- Histamine H1 Receptor Antagonist
 - Weak Dopamine Antagonist
 - Nausea and Vomiting
 - Motion Sickness
 - Respiratory Depression
 - Sedation
 - Anticholinergic Effects
 - Extrapyramidal Symptoms
 - Use Large Bore IV
 - Monitor for Tissue Necrosis
 
Hyperthyroidism Assessment
- Heat Intolerance
 - Exophthalmos
 - Warm, Moist Skin and Silky Hair
 - Tremors
 - Goiter
 - Diarrhea
 - Weight Loss
 - Tachycardia
 - Hypertension
 - Amenorrhea
 - Decreased TSH with Elevated Free T4
 - Radioactive Iodine Uptake (RAIU)
 
Hyperthyroidism Interventions
- Propylthiouracil (PTU)
 - Methimazole (Tapazole)
 - Iodine
 - Beta Blockers
 - Radioiodine Ablation
 - Thyroidectomy
 - Thyrotoxicosis
 - Post-Surgery Hypocalcemia
 
Propylthiouracil (PTU) and Methimazole (MMI)
- Hyperthyroidism
 - Inhibits Thyroid Peroxidase
 - PTU Blocks Peripheral Conversion of T4 to T3
 - Agranulocytosis
 - Skin Rash
 - Hepatotoxicity (PTU)
 - Teratogen (MMI)
 
Hypothyroidism Assessment
- Weight Gain - Edema
 - Lethargy
 - Cold Intolerance
 - Bradycardia
 - Hypertension
 - Brittle Nails and Dry Skin
 - Constipation
 - Goiter
 - Prolonged Menses
 - Slowed Thinking
 - Decreased Free T4
 - Increased TSH
 
Hypothyroidism Intervention
- Levothyroxine (Synthroid)
 - Liothyronine (Cytomel)
 - Myxedema Coma
 - Lifelong Replacement Hormone
 - Monitor Vital Signs
 - Fluids and Fiber
 - Low Calorie, Low Fat Diet
 - Medication Education
 - No Switching Brands
 
Levothyroxine (Synthroid)
- Synthetic T4
 - Hypothyroidism
 - Thyrotoxicosis
 - Tremors
 - Heat Intolerance
 - Insomnia
 - Tachycardia
 - Do Not Use for Obesity
 - TSH Monitoring
 
Phenylketonuria (PKU)
- Autosomal Recessive Genetic Disorder
 - Enzyme Deficiency
 - Failure to Thrive
 - Irritability
 - Musty or Mousy Odor
 - Cognitive Impairment
 - Low Phenylalanine Diet
 - Low Protein Foods (Diet)
 - Avoid Aspartame
 - Sapropterin (Kuvan)
 - Guthrie Blood Test