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Lehne's Pharmacology for Nursing Care, 10th Ed., Burchum & Rosenthal, 2019 | Registered Nurse (RN) School Study Aid


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86 - Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others
7 Picmonics to Learn | 13 mins

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Chloramphenicol (Chloromycetin)
Mechanism
Bacteriostatic
Indications
Gram Positive or Gram Negative Infections
Side Effects
Bone Marrow Suppression
Aplastic Crisis
Gray Syndrome
Considerations
Toxicity Limits Use
Monitor Blood Counts
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2 mins
Clindamycin
Mechanism
Bacteriostatic
Binds 50S Ribosomal Subunit
Indications
Gram-Positive Infections
Anaerobic Infections
Side Effects
Rash
Pseudomembranous Colitis
C. Difficile (Associated Diarrhea)
Arrhythmias
Blood Dyscrasias
Considerations
Monitor for Diarrhea
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3 mins
Macrolides
End in "-thromycin"
Mechanism of Action
Bacteriostatic
Indications
Alternative for Penicillin Allergy
Respiratory Infections
Pneumonia
Side Effects
QT Prolongation and Sudden Death
C.Diff Overgrowth
GI Distress
Considerations
Slow IV Infusion
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2 mins
Tetracyclines Overview
End in "-cycline"
Mechanism of Action
Bacteriostatic
Indications
Infectious Diseases
Acne
Periodontal Disease
Nursing Considerations
Avoid Milk, Antacids, Iron
Sunlight Protection
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1 min
Tetracyclines Side Effects
Side Effects
Superinfection
Clostridioides difficile
Discoloration of Teeth
Bone Deformities
Photosensitivity
Contraindications
Children Under 8
Pregnancy
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1 min
Macrolides Side Effects
Side Effects
Diarrhea
Prolonged QT Interval
P450 Inhibitor
Cholestatic Hepatitis
Skin Rash
Eosinophilia
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2 mins
Tetracycline Toxicities
Inhibition of Bone Growth in Children
Teratogen
Discoloration of Teeth
Photosensitivity
GI Distress
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2 mins

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