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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker
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Chapter 40: Drugs Affecting the Female Reproductive System

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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker | Registered Nurse (RN) School Study Aid

Chapter 40: Drugs Affecting the Female Reproductive System
11 Picmonics to Learn | 24 mins
Infertility
No Conception After 1 Year
Interventions
Artificial Insemination
In Vitro Fertilization (IVF)
Drug Therapy
Clomiphene Citrate (Clomid)
Menotropins
GnRH Agonists
Considerations
Treat Underlying Disorders
Emotional Support
Multiple Gestations
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3 mins
Oxytocin (Pitocin)
Mechanism of Action
Increase Uterine Contractions
Indications
Labor Induction
Control Postpartum Hemorrhage
Side Effects
Uterine Rupture
Water Intoxication
Contraindications
Fetal Lung Immaturity
Cervix Not Ripened
Active Genital Herpes Infection
Considerations
Use Lowest Dose
IV Pump
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3 mins
Posterior Pituitary
Characteristics
Neuroendocrine Reflex Stimulation (By Hypothalamus)
Direct Hormones
Vasopressin
Increased Water Retention (In Kidneys)
Oxytocin
Increased Uterine Contraction
Mammary Glands Contraction
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2 mins
Postpartum Hemorrhage
Mechanism
Uterine Atony
Lacerations
Retained Placenta
Signs and Symptoms
Bleeding
Hypotension
Boggy Uterus
Considerations
Oxytocin
Bimanual Compression of Uterus
Surgery
Blood Transfusion
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2 mins
Terbutaline (Brethine)
Mechanism of Action
Beta-2 Agonists
Indications
Asthma
Tocolytic
Side Effects
Hypotension
Tremor
Tachycardia
Pulmonary Edema
Hyperglycemia
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2 mins
Placenta Previa
Mechanism
Placenta Covers Cervical Os
Assessment
Painless
Bright Red Vaginal Bleeding
Interventions
Stable Fetus
Bed Rest
Observation
Unstable Fetus
C-section Delivery
Considerations
Risk for Shock
Magnesium Sulfate
Tocolysis
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3 mins
Clomiphene
Indications
Infertility
Polycystic Ovarian Syndrome (PCOS)
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Hypothalamus
Estrogen Antagonist
Increased GnRH, LH and FSH Secretion
Induction of Ovulation
Side Effects
Multiple Gestations
Visual Disturbances
Hot Flashes
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2 mins
Lab and Diagnostic Tests During Pregnancy (Other Visits)
Diagnosis
10-13 Weeks
Offer Chorionic Villus Sampling (CVS)
15-18 Weeks
Quad Screen
18-20 Weeks
Ultrasound
Anatomic Screening
24-28 Weeks
One-Hour Glucose Challenge Test
35-37 Weeks
Streptococcus Agalactiae
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3 mins
Quad Screen Results Interpretation
Markers
AFP
Estriol
hCG
Inhibin A
Associations
Increased hCG + Inhibin A (HIgh)
Down Syndrome
Decreased hCG + Estriol + AFP (Low HEAp)
Edward Syndrome
Increased AFP
Neural Tube Defects
Abdominal Wall Defects
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2 mins
Raloxifene
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Agonist in Bone
Antagonist in Breast and Uterus
Indications
Osteoporosis
Breast Cancer Prophylaxis
Uterine Fibroids
Side Effects
Hot Flashes
Thromboembolism
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2 mins
Ovulatory Hormones I - Follicular Phase
Characteristics
0-14 Days
GnRH Stimulates FSH and LH
Follicle Secretes Estrogen
Negative Feedback from Estrogen
Increased Estrogen Leads to Positive Feedback
FSH and LH Surge
LH Spike Leads to Ovulation
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2 mins

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